Cefazolin

Question 1

Cefazolin Trade Name?

Answer 1

Ancef, Kefzol

Question 2

Cefazolin Classification?

Answer 2

Cephalosporin antibiotic

Question 3

Cefazolin Mechanism?

Answer 3

binds to 1 or more penicillin-binding proteins, thereby arresting bacterial cell-wall peptioglycan biosynthesis and inhibiting bacterial replication

Question 4

Cefazolin Indications?

Answer 4

• Open fracture
• Amputation proximal to hand/foot
• Major soft tissue injury (exposed tendon or bone, large deep tissue laceration/avulsion,evisceration, major open crush injury, largely visible contaminated wounds excluding road rash)

Question 5

Cefazolin Contraindications?

Answer 5

-Known penicillin or cefazolin allergy
-Life threats not yet addressed
-Patient contact duration too short

Question 6

Cefazolin Side Effects/Precautions?

Answer 6

-Seizure
-abdominal cramps
-diarrhea
-nausea & vomiting
-skin rash
-pain at injection site

Question 7

Cefazolin Adult Dose?

Answer 7

Weight Based
>39kg - 2g slow IV/IO over 1-2 minutes
<39kg - 50mg slow IV/IO over 1-2 minutes
*CT protocols

Question 8

Cefazolin Pediatric Dose?

Answer 8

Weight Based
>39kg - 2g slow IV/IO over 1-2 minutes
<39kg - 50mg/kg slow IV/IO over 1-2 minutes
*CT protocols

Question 9

Cefazolin Onset of Action?

Answer 9

5 minutes
*medscape

Question 10

Cefazolin Duration of Action?

Answer 10

6-8 hours
*medscape

Question 11

Cefazolin Max Dose Adult/Pediatric?

Answer 11

6g/day (but not really an EMS consideration)
*pdr.net

Question 12

Cefazolin Routes of Administration?

Answer 12

IV/IO

Question 13

Cefazolin How Supplied?

Answer 13

500mg/10mL & 1g/10mL vials