Lymphatics (Ch 24) Flashcards
Functions of the Lymphatic System
- return excess fluid to bloodstream
- maintain blood volume level
- transport dietary lipids (waxes/fats - not absorbed by GI tract)
- generates immune response
- ->lymphacytes (WBCs) monitor blood/internal fluid to detect antigens
Lymph Vessels
merge to form lymphatic ducts/trunks
-reabsorb excess fluid and return it to venous circulation
Lymph
excess interstitial fluid and solutes (sometimes foreign material)
Lymph + Lymph Vessels =
- secondary venous drain system
- shortcut from capillary bed to the heart
Lymphatic Capillaries
one way valves that open for interstitial fluid, merge into lymphatic vessels
Lymphatic Ducts
responsible for draining specific parts of the body
- Thoracic Duct
- Right Lymphatic Duct
Thoracic Duct
starts in posterior abdomen as cistern chyli (large vessel that holds fluid, inferior to diaphragm) –> drains into L venous angle –> heart
*drains lymph from lower limbs, L abdomen, L thorax, L upper limb, L head/neck
Right Lymphatic Duct
*drains R upper limb, R thorax, R head/neck
Lymphedema
accumulation of fluid due to blocked lymph duct
What are the primary lymphatic organs?
- -> sites for lymphocyte formation/maturation
1. Red Bone Marrow
2. Thymus
Red Bone Marrow
- produce B and T cells
- B cells mature here
- located in long bones
Thymus
- located in anterior mediastinum, superior, covers great vessels and heart
- bilobed
- prominent in children –> atrophies –> replaced by adipose tissue
- T cells mature here
What are the secondary lymphatic organs?
- -> populated with lymphocytes from primary organs, series of filters for blood
1. Spleen
2. Lymph Nodes
3. Tonsils
Spleen
in abdomen on L side
- largest, destroys pathogens/old blood cells
- blood flows through, white pulp monitors for foreign materials –> red pulp destroys old RBCs
Lymph Nodes
circular nodules of lymphatic material distributed throughout body
- remove pathogens from lymph
- all over body: clusters at neck (cervical), armpits (axillary), groin (inguinal)
- lymph enters through vessels and exits out different vessels
- lymph seeps through sinuses in node = foreign materials destroyed/pathogens removed