LYMPH 2 Flashcards

1
Q

whats edema

A

Swelling caused by excess fluid trapped in body’s tissues (interstitial spaces)

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2
Q

where does edema effect the body

A

can affect any part of the body but is noticed more in your hands, arms, feet, ankles and legs

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3
Q

what is edema often associated with

A

any disease that causes salt retention and expansion of the extracellular fluid volume (renal, cardiac, and hepatic disease)

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4
Q

can edema occur without overall salt & water retention? why?

A

yes, because of microcirculatory alterations affecting Starling forces

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5
Q

what are the four lymphoid cells

A

lymphocytes, macrophages, dendritic cells, reticular cells

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6
Q

what are lymphocytes

A

main immune system warriors (T- and B- cells)
» Protect the body against antigens

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7
Q

what are macrophages

A

Phagocytize foreign substances; Activate T cells

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8
Q

what are dendritic cells

A

Capture, process, and present antigens to T cells for activation

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9
Q

what are reticular cells

A

Produce reticular fiber network that supports other cells in lymphoid tissue

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10
Q

what is lymphoid tissue composed of

A

reticular connective tissue (in thymus)

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11
Q

what cells are constantly entering and leaving the lymphoid tissue

A

lymphocyes

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12
Q

what does the lymphoid tissue house and provide

A

an activation/proliferation site for lymphocytes

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13
Q

what does the lymphoid tissue do for immune cells

A

Gives a good surveillance vantage point

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14
Q

what are the two types of lymphoid tissues

A

diffuse lymphoid tissues and lymphoid follicles

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15
Q

describe diffuse lymphoid tissue

A

loose arrangement of cells and fibers in almost all organs

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16
Q

describe lymphoid follicles

A

solid, spheres of tightly packed lymphoid cells and fibers

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17
Q

what are the two categories of lymphoid organs

A

primary organs and secondary organs

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18
Q

what happens in primary organs

A

B and T cells mature; contains red bone marrow and thymus

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19
Q

whats the red bone marrow

A

origination site for both cells; maturation site for B cells

20
Q

whats the thymus

A

maturation site for T cells

21
Q

what happens at secondary organs

A

where lymphocytes encounter antigens and are activated

22
Q

what are some examples of secondary organs

A

Lymph nodes, spleen, tonsils, Peyer’s patches (small intestine), appendix

23
Q

what cleanses lymph

A

only lymph nodes

24
Q

what are the two basic functions of lymph nodes

A

cleanse lymph and immune system activation

25
how do macrophages cleanse lymph
Macrophages remove and destroy microorganisms and harmful debris, so they are not transferred back into the bloodstream/body
26
how do lymph nodes work to activate the immune system
Strategically located sites where dendritic cells bring back antigens to activate T cells
27
describe the structure of lymph nodes
bean shaped and less than 1in long; Surrounded by connective tissue capsule that extends inwards; cortex, medulla, lymph sinuses
28
describe cortex of lymph nodes
superficial, densely packed region - Contains dividing B cells, dendritic cells, and transient T cells
29
describe medulla of lymph nodes
inner region containing T and B cells
30
describe lymph sinuses of lymph nodes
large lymphatic capillaries containing macrophages for lymph filtering
31
what does the Mucosa-associated lymphatic tissue (MALT) protect
protects passages that are open to the exterior; includes tonsils, appendix, Peyer's patches
32
what do tonsils do
remove pathogens that enter through food or air
33
whats the largest lymph organ in body
spleen
34
whats the spleen the site for
lymphocyte proliferation
35
what does the spleen do for blood
filters blood and gets rid of old, defective RBCs and platelets
36
what does spleen do for RBC products
recycles for future use
37
what does spleen release
break down products to blood for processing by liver
38
what does spleen store
some iron from hemoglobin and platelets and monocytes until needed
39
what are the two sections of the spleen
red pulp and white pulp
40
what happens at the white pulp
immune function takes pace
41
what happens at the red pulp
blood filtering takes place
42
when does thymus function
primarily early in life; atrophy at puberty
43
what happens at the thymus
T-cells mature
44
what is the thymus gradually infiltrated with
adipose tissue
45
what do epithelial cells of the thymus secrete
thymosin and thymopoietin
46
whats thymosin
stimulates T cell development
47
whats thymopoietin
indues proliferation of lymphocyte precursors and differentiation into T cells