BODY FLUID + ELECTROLYTE BALANCE 1 Flashcards

1
Q

why do men have more water than women

A

men have more water bc more muscle mass + women carry more fat

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2
Q

order the following tissues From most to least hydrated: skeletal muscle > bone > adipose

A

Skeletal muscle > bone > adipose

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2
Q

what are the two compartments of total body fluid

A

Intracellular fluid (ICF)
Extracellular fluid (ECF)

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3
Q

what makes up intracellular fluid (ICF)

A

2/3rd water volume; 40% of body weight

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4
Q

what makes up ECF

A

Consists of plasma and interstitial fluid (IF)
- 1/3rd water volume

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5
Q

whats interstitial fluid

A

fluid around cells; 80% of ECF

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6
Q

whats plasma

A

20% of ECF

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7
Q

what are electrolytes

A

Dissociate into ions in solution; can conduct electricity

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8
Q

do electrolytes have Greater ability to change osmolarity than nonelectrolytes

A

yes

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9
Q

what does increased osmolarity indicate

A

increased solutes

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10
Q

are electrolytes polar

A

yes

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11
Q

what are examples of electrolytes

A

inorganic salts (NaCl), acids and bases, some proteins

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12
Q

what are nonelectrolytes

A

Do not dissociate in solution; cannot conduct electricity

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13
Q

are non electrolytes polar or nonpolar

A

nonpolar

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14
Q

what are somme examples of nonelectrolytes

A

glucose, lipids, creatine, urea

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15
Q

what are the primary cation and anion in ECF

A

 Na+ is the primary cation
 Cl- is the primary anion

16
Q

what are the primary cation and anion in ICF

A

 K+ is the primary cation
 Hydrogen phosphate (HPO42-)
is the primary anion

17
Q

what does ICF contain in addition to the K+ and hydrogen phosphate?

A

many proteins

18
Q

what are some examples of water losses

A

insensible water loss, sweat, fecal losses, urine

19
Q

what are some examples of water intake

A

fluid intake, water from food, metabolic water

20
Q

what must be maintained for water balance regulation

A

Must maintain ECF osmolality concentration

21
Q

what happens when there’s an increase in plasma osmoality

A

→ Triggers thirst → drink fluids
→ Release of anti-diuretic hormone (ADH) → kidneys reabsorb water

22
Q

what happens when there’s a decrease in plasma osmolality

A

→ Inhibits thirst
→ Inhibits ADH → large outputs of dilute urine

23
Q

what happens to cells in hypo-osmolality

A

swollen and ruptured

24
Q

what happens to cells in hyper-osmolality

A

dried out and shrunken

25
Q

what happens to cells in iso-osmolality

A

happy

26
Q

when we’re deprived of water, our plasma osmolarity goes up, which stimulates our osmoreceptors in the anterior hypothalamus. what does this result in

A

increase in thrist
and ADH secretion from posterior pituairty

27
Q

what happens after ADH is secreted

A

increase in H2O permeability in distantl tubule and collecting duct, which results in ann increase in water reabsoprtionm and increase in urine osmolarity and decrease in urine volumme

28
Q

when we have too much water, our plasma osmolarity goes down, which inhibits our osmoreceptors in the anterior hypothalamus. what does this result in

A

decrease in thrist and decrease in ADH which does the opposite of what was said before

29
Q

what is thirst regulated by

A

hypothalamic thirst center

30
Q

what is the hypothalamic thrist center activated by

A

osmmoreceptors, dry mouth and decreased blood volume

31
Q

what do osmoreceptors detect and how

A

detect ECF osmolality
 Gain or loss of water causes plasma membrane stretch

32
Q

what does dry out do to osmotic pressure

A

Increased osmotic pressure leads to less saliva production

33
Q

what is decreased blood volume or pressure detected by

A

baroreceptors

34
Q

when is the thirst center inhibited

A

prematurely; before fully hydrated

35
Q

whats insensible water loss

A

unavoidable water loss in skin and lungs

36
Q

whats sensible water loss

A

(urine)
 Minimum urine output: 500ml/day
 Necessary to flush end products of metabolism

37
Q

whats urine output beyond necessity determined by

A

fluid intake, diet, and other water loss