LYMPH 1 Flashcards

1
Q

what does the lymphatic system consist of

A

lymphatic vessels and various lymphoid tissues and organs scattered throughout the body

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2
Q

why does fluid leak out of capillary bed

A

pressure in beginning part of capillary bed
is greater than surrounding tissue; as a result,
fluid leaked out; most fluid is reabsorbed, but not all up to lymphatic system to pick the rest up

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3
Q

what does the lymphatic system drain

A

Drain body fluids and return to bloodstream to maintain blood volume

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4
Q

what does the lymphatic system transport

A

dietary lipids (and lipid-soluble vitamins)

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5
Q

what does the lymphatic system facilitate

A

immune responses (i.e., initiate highly specific responses directed against particular microbes or abnormal cells)

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6
Q

is the lymphatic system one way

A

yes

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7
Q

whats the pathway for lymphatic system
CICVTDS

A

Blood capillaries → Interstitial spaces → Lymphatic capillaries → Lymphatic vessels → Lymphatic trunks → Lymphatic ducts → Subclavian veins

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8
Q

how do lymphatic capillaries compare to blood capillaries

A

slightly larger

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9
Q

are lymphatic capillaries permeable

A

yes

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10
Q

where are lymphatic capillaries located

A

Located everywhere except CNS, bone marrow, bones, teeth, cornea

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11
Q

what area are lymphatic capillaries located

A

where interstitial fluid enters lymphatic
system

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12
Q

what about endothelial cells makes lymphatic capillaries permeable

A

Endothelial cells are not tightly joined, so edges of cells are loosely overlapped creating valves

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13
Q

what does collagen do to endothelial cells

A

collagen anchors the endothelial cells (walls) to surrounding structures

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14
Q

what does collagen anchoring endothelial cells allow for

A

allows for any increase in interstitial fluid to put pressure on the valves and open them

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15
Q

what happens when interstitial fluid pressure > capillary fluid pressure

A

Flap opens and lymph enters lymphatic capillaries

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16
Q

what happens when capillary fluid pressure > interstitial fluid pressure

A

flaps close

17
Q

why is the permeability of lymphatic system a double-edge sword

A

Proteins enter easily, along with pathogens, cell debris and cancer cells (double-edged sword)

18
Q

what are lacteals

A

Highly specialized lymphatic capillaries in the intestinal mucosa

19
Q

what do lacteals play a major role in

A

absorbing digested fats/capturing fat

20
Q

what is the lymph in lacteals called

A

chyme, with a milk color because of high fat content (instead of being transparent)

21
Q

where do lacteals sit

A

alongside microvilli

22
Q

how are initial lymphocytes different from capillaries

A

have many inter- endothelial junctions

23
Q

what do lymphocyte vessels do

A

Act as one-way microvalves (primary lymph valves)

24
Q

what do the walls of larger collecting lymphocytes contain

A

consisting of endothelium and sparse smooth muscle

25
Q

what do larger lymphatic vessels have, and what does this restrict

A

secondary lymph valves (like veins)
Restrict retrograde movement of lymph