Lithium Orotate Flashcards
Alkali metal, naturally present in trace amounts in minerals, water, soil, and in fruits, vegetables
Lithium
Needed for proper function of enzymes, hormones, vitamins, growth factors, immune and nervous system
Lithium
Glutamate-induced excitotoxicity mediated by N-methyl-D-asparatate (NMDA) receptors:
Decreased
Influx of calcium
Inhibited
Mood disorders, Anxiety, Anorexia, Schizophrenia, Alcoholism, Epilepsy, Alzheimer’s, Parkinson’s, ALS and Huntington’s, Stroke, Heart attack, Diabetes, Cancer, Meniere’s Disease, Inflammatory and Autoimmune diseases:
Helps with
Heat Shock Proteins:
Increased
Promote folding of proteins, refolding of misfolded proteins and disposal of abnormal proteins:
Heat Shock Proteins
GSK-3:
Inhibited
Protein in the frontal cortex that protects from apoptosis
Bcl-2
Bcl-2:
Increased
BDNF:
Increased
Nerve Growth Factor:
Increased
Glial-Derived Neurotrophic Factor:
Increased
Promotes cell growth and remodeling of the blood vessels after stroke
VEGF
VEGF:
Increased
Autophagy:
Increased
Stimulate progenitor and stem cells in cultured brain hippocampal neurons:
Lithium
N-acetyl aspartate:
Increased
Marker of creativity and is correlated with IQ scores:
N-acetyl aspartate:
Long-term potentiation (LTP) in the hippocampus:
Increased
exploratory activity and aggression
Decreased
Calmness:
Increased
Mood:
Improved
Suicide rates:
Decreased
Serotonin synthesis and release:
Increased
Norepinephrine:
Decreased
CCK in the brain:
Increased
Serotonin 5-HT1A postsynaptic sensitivity:
Increased
Insulin-stimulated glucose transport and glycogen synthesis
Enhanced
Insulin release:
Decreased
Immunity:
Improved
Th1 cells and Interferon gamma:
Suppressed
Inflammation:
Decreased
IL-1β and TNF-α:
Decreased
IL-2, TGF, IL-1RA and IL-10:
Increased
IgG and IgM antibodies
Increased
Production and activity of prostanglandins
Decreased
Frequency and duration of labial and genital herpes:
Decreased
Occurrence of common colds
Decreased
Risk of bone fractures:
Decreased
Bone formation
Increased
Circadian rhythm
Lengthened
Mitochondrial energy output
Increased
Life-span:
Increased
Turnover of dysfunctional mitochondria:
Increased
NAD+:
Increased
Severity of tardive dyskinesia:
Decreased
Involuntary movements:
Improved
Symptoms of OCD:
Decreased
Severity of both chronic and episodic cluster headache
Decreased
Vasopressin:
Increased
Grey matter:
Increased
Toxins in brain:
Removed
Neuronal damaging proteins:
Inhibited
Most well-absorbed than lithium carbonate and lithium chloride:
Lithium orotate
Anxiety:
Decreased
Beta-amyloid secretion:
Inhibited
Chelates:
Aluminum