Divalproex sodium Flashcards

1
Q

Seizures:

A

Decreased

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2
Q

GABA:

A

Increased

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3
Q

Mitogen-activated protein kinase-extracellular signal-regulated kinase:

A

Activated

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4
Q

Histone deacetylase:

A

Inhibited

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5
Q

Mood:

A

Stabilized

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6
Q

Neuroprotection:

A

Increased

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7
Q

BDNF:

A

Increased

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8
Q

Melatonin MT1 receptor:

A

Increased

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9
Q

Synergistic with:

A

Melatonin, Nifedipine,

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10
Q

Dispepsia, Diarreia, Tremor, Seda-
ção, +TGP, -Leuco,
-Plaq, Perda de cabelo e +Peso:

A

Adverse effects

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11
Q

Neuropeptide Y:

A

Increased

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12
Q

Voltage-dependent Sodium channels:

A

Blocked

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13
Q

Conditioned fear:

A

Decreased

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14
Q

Alzheimer:

A

Controlled

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15
Q

Excitotoxicity:

A

Decreased

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16
Q

Oxidative stress:

A

Decreased

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17
Q

Dopaminergic neurons in midbrain:

A

Protected

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18
Q

Proteina-quinase C:

A

Decreased

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19
Q

Cognitive dysfunction induced by d-amphetamine:

A

Decreased

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20
Q

Glutamate receptor expressions:

A

Regulated

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21
Q

Hippocampal neurogenesis:

A

Increased

22
Q

Axonal regeneration:

A

Increased

23
Q

Inositol:

A

Depleted

24
Q

Oxygen-glucose deprivation injury:

A

Decreased

25
Q

Lifespan of cortical neurons:

A

Increased

26
Q

Neurons exposed to hemorrhage or ischemia:

A

Protected

27
Q

Transcription factor CREB

A

Activated

28
Q

CREB:

A

cAMP response element

binding protein

29
Q

Pro-apoptotic molecules:

A

Inhibited

30
Q

Microglia-mediated inflammation:

A

Decreased

31
Q

Blood-Brain Barrier permeability:

A

Decreased

32
Q

Cognitive dysfunction induced by TBI:

A

Decreased

33
Q

Glycogen synthase kinase-3:

A

Activated

34
Q

Bcl-2:

A

Increased

35
Q

Pain:

A

Decreased

36
Q

Migraine:

A

Decreased

37
Q

Inflammation:

A

Decreased

38
Q

Glycine:

A

Increased

39
Q

Taurine:

A

Increased

40
Q

Glutamic acid decarboxylase:

A

Enhanced

41
Q

CSF:

A

Increased

42
Q

Extracellular Serotonin:

A

Increased

43
Q

Extracellular Dopamine:

A

Increased

44
Q

CNS axons:

A

Regenerated

45
Q

Grey matter volume:

A

Increased

46
Q

Brain N-acetyl aspartate:

A

Increased

47
Q

Neuritogenesis:

A

Increased

48
Q

Neural cell adhesion molecules:

A

Increased

49
Q

Learning:

A

Increased

50
Q

Memory:

A

Improved

51
Q

Microtubule formations:

A

Stabilized