Dopamine Flashcards
Definition:
Catecholamine neurotransmitter
Pleasure, Motivation, Decision making, Motor control, Hormonal release:
Effects
Brain structure linked to pleasure:
Nucleus accumbens
Precursors:
L-Phenylalanine, L-Tyrosine and L-Dopa
Effects in the blood vessels:
inhibits norepinephrine release and acts as a vasodilator (at dopaminergic concentrations)
Dopaminergic receptors action:
Vasodilation
Effect in the pancreas:
Reduces insulin production
Effects in the digestive system:
Reduces gastrointestinal motility and protects intestinal mucosa
Effects in the immune system:
Reduces the activity of lymphocytes
Decreased dopamine activity disorders:
Parkinson’s disease, Restless legs syndrome and ADHD
Increased dopamine activity disorders:
Schizophrenia
Activities that increases dopamine:
Exercise, Sex,
Drugs that increase dopamine:
Amphetamine, Methylphenidate
Cofactors:
B6
“DOPAMINE”:
Drive, psychOsis, Parkinsonism, Attention, Motor, Inhibition of prolactin, Narcotics and Extrapyramidal