lipids Flashcards

1
Q

are lipids water soluble?

why are they not considered polymers?

A

no

Lipids are not considered polymers because they do not consist of repeated monomer units linked together through covalent bonds, which is a defining characteristic of polymers. Instead, lipids are a diverse group of organic molecules that have unique and variable structures.

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2
Q

polymers

A

a uniform repetition of monomeric units.

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3
Q

what are the main biological functions of lipids?

A

Energy storage
Heat/Insulation
Structural components of cell membrane communication

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4
Q

name the types of lipids

A

Fatty acids
Triacylglycerols
Phospholipids
Sphingolipids
Steroids

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5
Q

what is the general formula for fatty acids?

what do we mean when we say fatty acids are amphipathic?

A

H(CH2)nCOOH

means they have both hydrophilic and hydrophobic regions

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6
Q

what is the typical range for the number of carbons in fatty acid chains that are found in plants and animals?

A

between 16 and 18

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7
Q

by what means are lipids mostly circulated around the body

A

by being bound to albumin

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8
Q

what are fatty acids found at high levels in the plasma during fasting?

A

The increase in fatty acids in the plasma during fasting is directly connected to the process of lipolysis. Lipolysis is the biochemical process by which stored triglycerides (fat) in adipose tissue are broken down into their constituent fatty acids and glycerol. These released fatty acids are then released into the bloodstream, leading to higher plasma levels of free fatty acids (FFAs) during fasting. this helps to produce energy

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9
Q

features of saturated fatty acids

A

they have only single bonds between their carbons
they have a linear appearance
they are solid at room temperature

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10
Q

features of unsaturated fatty acids

A

One or more C=C bonds
They have C=C double bonds that give distinct bend
Reduces Tm(melting point), therefore, they are liquid at room temp

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11
Q

what effect does a low saturation have on the melting point of fatty acids

A

it results to a low melting point

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12
Q

Describe the composition of triglycerides(triacylglycerols) (TAGs)

A

Glycerol head group attached to 3 fatty acid chains

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13
Q

how are TAGs stored?

A

they are stored as cytoplasmic lipid droplets

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14
Q

enzyme that hydrolyses lipids into glycerol and 3 fatty acids

A

lipase

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15
Q

homogenic fatty acids

heterogenic fatty acids

A

fatty acids of the same structure

fatty acids of different structures

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16
Q

saturated fats

example

A

fats composed of saturated fatty acids

most animal fats

17
Q

examples of unsaturated fats

A

plant and fish fats (aka oils)

18
Q

where in mammals are fats stored?

A

in the adipose tissue

19
Q

which stores more energy, carbohydrates or fats

A

fats store double the amount of energy that carbohydrates store

20
Q

composition of phospholipids

A

glycerol, two fatty acids and a phosphate group

21
Q

sphingolipid composition

A

sphingosine, one fatty acid, and an R-group

22
Q

functions of sphingolipids

A

Cell recognition
Cell Signaling
Lipid rafts

23
Q

steroids

A

Steroids are lipids with a common carbon skeleton consisting of four fused carbon rings

24
Q

what results to there being different steroids

A

different functional groups being attached to the rings

25
Q

what is the base for all steroid hormones and bile acids

A

cholesterol

26
Q

name some steroid hormones

A

cholesterol
Oestrogen
testosterone
progesterone
Glucocortecoids

27
Q

where in the mammalian system is cholesterol synthesized

A

the liver

28
Q

what is the total average body composition of cholesterol?

what percentage of this is part of the cell membrane structure

A

150g

90 percent

29
Q

lipid transport is undertaken by

A

apolipoproteins

30
Q

briefly describe lipid transport

A

Dietary lipids are transported from the intestine to the liver (exogenous)

Lipids are then transported from the liver to peripheral tissues (endogenous)

31
Q

what are the classes of lipoproteins?

A

Chylomicron
VLDL(Very Low-Density Lipoproteins)
LDL(Low-Density Lipoproteins)
HDL(High-Density Lipoproteins)

32
Q

which one of the classes of lipoproteins has the lowest density(i.e low protein: lipid ratio)

A

chylomicrons

33
Q

which one of the classes of lipoproteins has the highest weight of triacylglycerols

A

chylomicrons

34
Q

which one of the classes of lipoproteins has the second highest triacylglycerols as % of weight

A

VLDL

35
Q

glyceride

A

type of lipid composed of glycerol and fatty acids

36
Q
A