Lipid metabolism Flashcards
receptors for chylomicron remnants
ApoE specific
VLDL remnant maybe converted into
LDL
chylomicron remnants are CATABOLIZED where
liver
elevated plasma level projects against artherotherosclerosis
HDL
cholesterol is transported from liver to extrahepatic tissues
LDL
triglycerides are transported from liver to extrahepatic tissues
VLDL
nascent chylomicron receives apolipoproteins C& E from
HDL
apolipoprotein B-100 is present in
VLDL&LDL
apolipoprotein B-48 is present in
chylomicrons
familial hypercholesterolemia is associated with
increased LDL concentration
conversion of fatty acyl-CoA derivative having 2 more carbon atoms involves as acetyl donor
Malonyl-CoA
the rate limiting step of cholesterol biosynthesis is
HMG CoA reductase
compound normally used to conjugate bile acids is
glycine
B-oxidation of fatty acid chain produces
propionyl CoA
chain elongation of fatty acids occurring in mammalian liver takes place in which of the following subcellular factions of the cell
microrosomes
LCAT is
lecithin cholesterol acyl transferase
the protein which is infact a multifunctional enzyme complex in higher organism is
fatty acid synthesis
class of lipoproteins having a beneficial effect in artherosclerosis is
HDL
the major source of cholesterol in arterial smooth muscle cells is from
LDL
long chain fatty acyl CoA esters are transported across the mitochondria membrane by
carnitine