2nd sem: Hormones 1 Flashcards

1
Q

norepinephrine derived from

A

amines

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2
Q

TSH is derived from

A

polypeptide

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3
Q

estradiol is derived from

A

steroids

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4
Q

hormone that is produced in final form and used immediately

A

aldosterone

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5
Q

hormone produced in final form and stored in same cell

A

norepinephrine

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6
Q

hormone that is converted in the periphery

A

T3 & T4

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7
Q

hormone that is cleaved from large precursor into active hormone

A

Glucagon

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8
Q

group of hormones with short plasma half life

A

group 2 hormones

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9
Q

group of hormones that binds to intracellular receptors

A

group 1

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10
Q

group of hormones that second messengers carry out response desired

A

group 2

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11
Q

hormones that co-activators needed to activate target gene

A

group 1

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12
Q

estrogen belongs to what group of hormones

A

group 1

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13
Q

opioids belongs to what group of hormones

A

group 2

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14
Q

opioids mechanism of action

A

adenylate cyclase inhibition

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15
Q

parathyroid mechanism of action

A

adenylate cyclase activation

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16
Q

erythropoietin mechanism of action

A

tyrosine kinase

17
Q

GnRH mechanism of action

A

phosphoinositide turnover

18
Q

in the synthesis of polypeptide proteins, removal of the signal peptide produces the____

A

prohormone

19
Q

the receptor-hormone which binds to specific DNA sequences called hormone response elements are utilized by what particular types of hormones

A

lipid soluble hormones

20
Q

the enzyme system catalyzes the conversion of ATP to cyclic AMP

A

Adenylate cyclase

21
Q

GnRH stimulates the release of

A

LH and FSH

22
Q

the DNA binding domain is found in the

A

intracellular receptor

23
Q

group of steroids with 21 carbons

A

progesterone

24
Q

modification of the functional group on the D ring of the steroid nucleus would yield

A

androgens

25
Q

Where are glucocorticoids synthesized in your adrenal cortex?

A

ZONA FASICULATA

26
Q

What process does progesterone undergo to be converted into cortisol?

A

hydroxylation reactions

27
Q

How many carbons does estrogens have?

A

18 carbons

28
Q

From corticosterone, by action of aldosterone synthase, what group is added?

A

Carbonyl oxygen (happens in the zona glomerulosa)

29
Q

when 17,20 lyase removes 2 carbons, what will be the type of hormone produced?

A

androgens (from 21 carbons -> 19 carbons)

30
Q

Ano ang mas potent?
Dihydrotestosterone
Testosterone

A

DIHYDROTESTOSTERONE

31
Q

What stimulates the zona glomerulosa to produce the specific hormones?

A

angiotensin II
K+
ACTH

32
Q

What is the active form of vitamin D?

A

1,25 cholecalciferol or CALCITRIOL

33
Q

from precursor proteins and peripheral activation

A

T3 and DHT