2nd sem: Hormones 1 Flashcards
norepinephrine derived from
amines
TSH is derived from
polypeptide
estradiol is derived from
steroids
hormone that is produced in final form and used immediately
aldosterone
hormone produced in final form and stored in same cell
norepinephrine
hormone that is converted in the periphery
T3 & T4
hormone that is cleaved from large precursor into active hormone
Glucagon
group of hormones with short plasma half life
group 2 hormones
group of hormones that binds to intracellular receptors
group 1
group of hormones that second messengers carry out response desired
group 2
hormones that co-activators needed to activate target gene
group 1
estrogen belongs to what group of hormones
group 1
opioids belongs to what group of hormones
group 2
opioids mechanism of action
adenylate cyclase inhibition
parathyroid mechanism of action
adenylate cyclase activation
erythropoietin mechanism of action
tyrosine kinase
GnRH mechanism of action
phosphoinositide turnover
in the synthesis of polypeptide proteins, removal of the signal peptide produces the____
prohormone
the receptor-hormone which binds to specific DNA sequences called hormone response elements are utilized by what particular types of hormones
lipid soluble hormones
the enzyme system catalyzes the conversion of ATP to cyclic AMP
Adenylate cyclase
GnRH stimulates the release of
LH and FSH
the DNA binding domain is found in the
intracellular receptor
group of steroids with 21 carbons
progesterone
modification of the functional group on the D ring of the steroid nucleus would yield
androgens
Where are glucocorticoids synthesized in your adrenal cortex?
ZONA FASICULATA
What process does progesterone undergo to be converted into cortisol?
hydroxylation reactions
How many carbons does estrogens have?
18 carbons
From corticosterone, by action of aldosterone synthase, what group is added?
Carbonyl oxygen (happens in the zona glomerulosa)
when 17,20 lyase removes 2 carbons, what will be the type of hormone produced?
androgens (from 21 carbons -> 19 carbons)
Ano ang mas potent?
Dihydrotestosterone
Testosterone
DIHYDROTESTOSTERONE
What stimulates the zona glomerulosa to produce the specific hormones?
angiotensin II
K+
ACTH
What is the active form of vitamin D?
1,25 cholecalciferol or CALCITRIOL
from precursor proteins and peripheral activation
T3 and DHT
