Conference: apoptosis and cell necrosis

Question 1

this is the breakdown of the protein-rich cytoskeleton by the caspases

Answer 1

cell shrinkage

Question 2

when a cell detaches its cytoskeleton causing the membrane to sell into spherical bubbles

Answer 2

Blebbing

Question 3

with inflammation, eliminated debridement, affects group of contagious cells

Answer 3

necrosis

Question 4

with localized effects that destroys individual cells, genetically programmed, and energy (ATP)-dependent

Answer 4

apoptosis

Question 5

no membrane blebbing, has cell swelling and lysis and is pathological only

Answer 5

necrosis

Question 6

membrane blebbing occurs, no inflammatory response, requires energy

Answer 6

apoptosis

Question 7

known as the mitochondrial pathway, initiated by exposure to ROS, uses CASPASE-9 as an initiator

Answer 7

intrinsic pathway

Question 8

uses CASPASE-8 as an initiator also known as death receptor pathway

Answer 8

extrinsic pathway

Question 9

this inhibits the conversion of procaspase-3 to its active form

Answer 9

Inhibitors of apoptosis (IAPs)

Question 10

this inhibits the conversion of procaspase-8 to its active form (caspase-8)

Answer 10

FLICE-inhibitory protein (FLIP)

Question 11

activation of this gene upregulates transcription of BAX

Answer 11

p53

Question 12

inhibits loss of membrane potential, it is antiapoptotic

Answer 12

BCL-2

Question 13

this expression is increased on monocytes, macrophages and natural killer cells

Answer 13

FasL expression

Question 14

this expression in increased in CD4 and CD8-positive T cells and B cells

Answer 14

Fas expression