1st semester: special tissues Flashcards
patients with osteoarthritis has decrease in which GAG
chondroitin sulfate
excessive sagging of the skin, down slanting of palpebral fissure, what happened?
there is a fragmentation of elastin
crouzon syndrome has mutation in which receptor
FGFR 3
a patient has hyposcoliosis, exhibits joints hyper mobility and tendency to ocular rupture/ the signs and symptoms of the disease is most likely
lysyl hydroxylase
thumb and index finger overlap when encircling opposite wrist is known as what sign
walker murdoch sign
a 5 yearold boy with normal developmental milestone, presented has frontal bossing, hypertelorism, wide and broad nasal bridge, giginval hypertrophy, associated with hepatosplenomegaly, and umbilical hernia, eye examination revealed (+) corneal clouding. this condition is due to which lysosomal hydrolase(MAROTEAUX-LAMY SYNDROME)
N-acetygalactosamine 4 sulfate
a 7 year old with delayed developmental milestone, has frontal bossing, hypertelorism, wide and broad nasal bridge, giginval hypertrophy, associated with hepatosplenomegaly, and umbilical hernia, eye examination revealed (-) corneal clouding. this condition is due to which lysosomal hydrolase(hunters)
iduronate sulfate
a patient has thinning of skin, very visible blood vessels, this patient has the increase odds of having spontaneous rupture of arteries
TYPE 3
what factor would stimulate osteoblastic activity
calcitonin
true or false, does collagen has repeating gly-X-Y repeating structure while elastin has no repeating structures
TRUTH BESH
TRUE OR FALSE, type 3 collagen, chondrotin sulfate content is higher in keloid that in normal scar
true
TRUE OR FALSE, collagen cross-linking is greater than in keloid than in normal scar
false
patients with artherosclerosis has an increase in what GAG
dermatin sulfate
most abundant protein in the extracellular matrix
collagen
what are the specialized proteins
fibronectin and laminin
