Lecture 7

Question 1

____ is the drug used to treat CF arising from the deltaF508 mutation, ____ is the drug used to treat CF arising from the G511D mutation, and ____ is the “combination” drug.

Answer 1

Lumacaftor for deltaF508, Ivacaftor for G511D, and Orkambi for the combo.

Question 2

____ is the drug that restores crystallin function in the lens and fixes aggregation.

Answer 2

Lanosterol