Lecture 5 (Hepatic Portal, Fetal and Lymphatic Circulation) Flashcards
Hepatic Portal Circulation
Carries nutrients from the stomach and intestines to the liver for completion of digestion
Hepatic Veins
NOT RELATED TO PORTAL CIRCULATION
Drain the liver to the inferior vena cava
Hepatic Portal veins
- Superior Mesenteric Vein (Drain small intestine and 2/3rds of the colon)
- Inferior Mesenteric vein (Drains rest of colon and rectum
- Splenic Vein (Drains the spleen, stomach and pancreas
The Spleen
Checks ages of red blood cells, takes out the old ones, recycles iron and protein
Removed: Liver takes over
Splenic Blood: if punctured by a broken rib, you will bleed out rapidly
Hematogenous spread of cancer
Cancer transported by the blood, metastisis by the blood
Heaptic portal veins can do this
Pancreatic cancer -> move into the liver
Colon cancer -> mesenteric veins -> go to the liver
5 specializations of the unborn child
- Umbilical veins (Oxygenated blood from placenta)
- Ductus veinosis: In the lover brings blood to the inferior vena cava
- Foramen (opening) Ovale: Sends blood to right atrium to the left atrium
- Ductus Arterious: Skips the pulmonary trunk and sends blood to the aorta
- Two Umbilical veins: starts at the internal iliac arteries, have very little oxygen and are waste, send out to the placenta for waste removal
5 events following birth
- Ductus arteriosus contracts: Plumonary trunk blood circulates to lungs (Ligamentum arteriosum)
- Foramen Ovale: closes within 1 year = fossa ovalis
- Umbilical Vein: forms the ligamentum teres
- Ductus Vensosus: froms the ligamentun Venosum
- Umbilical arteries: Form umbilical ligaments
Atrial septal defect (ASD)
Patent (open) foramen ovale
Hole in the wall
blood travels back and forth btw R. atrium and L. atrium
Ventrical Septal defect
Improper heart formation
Extremely bab cannot be repaired
Most babies die, born blue
ASD Fix
path over the hole, larger than the hole (because of growth as a kid and in adol.)
Put on the left side has much more pressure keeping the patch in place
Lymphatic Circulation
Lymph capillaries collect excess tissue fluid -> lymphatic veins -> through lymph nodes -> r lymphatic duct (upper body, right head and neck right thorax -> thoracic lymphatic duct (drains remainder of body) -> internal jugular/ subclavian veins
Lymph Nodes
Responds to infection
Trying to break it down
First line of defense is neutrophils
Lymphocytes are next
Cancers
Abnormal cell division
lymph nodes do not react to cancer because the cell is not foreign
Cancer passes through lymph nodes
Lymph Node inspection
Lymph node adjacent to the tumor is inspected
If it’s in the lymph then we know it has spread
Lymphatic Metastasis
Breast Cancer
May enter into the axillary lymph N. may enter other nodes