Lecture 2 (Embryology, cells, and Skin) Flashcards
Anatomy Types
Anatomy: "to cut apart" Gross: body or organs with naked eye Microscopic Development: embryology Pathological: Abnormalities
Major organ systems (11)
Organs are made of tissues which are made of cells
- Integument
- skeletal
- articulations (joints)
- muscular
- circulatory
- respiratory
- digestive
- urinary
- nervous (sense organs)
- endocrine
- Reproudctive
Integument
Skin, hair, nails
Skeletal
Bones and cartilage
Circulatory
Heart, arteries, capillaries, veins
Respiratory
Nose, larynx, lungs
Digestive
Mouth, pharynx, intestines, glands of this system
Urinary
Kidney, bladder
Nervous system
Senses, taste and smell, perception, sense organs (eye, ear, smell, taste, pain, temperature, and proprioception)
Endocrine
hormones
Reproductive
Male and female
Articulation
Joints and Ligaments
3 primary germ layers
- Ectoderm
- mesoderm
- endoderm
Ectoderm
Outer most layer of skin
Cells divide very rapidly and make many functions
Brain and spinal column are also made from this (entire nervous system)
Mesoderm
Middle layer of skin
Muscles that attach to bones, the bones, the heart, blood vessels, kidney
Endoderm
Innermost layer
Respiratory system, digestive and it’s gland
Cells
Some cells have no nucleus (Blood cells)
marrow, contain many nuclei
Nuclei can have diff shapes (help with ID)
Smooth Endoplasmic reticulum
Helps with neutralizing of poisons
Mitochondria
Production of ATP, Especially in cells that contract
Microvilli
Cilia that are really small
Flagella
The long tail of sperm
Pigment
Melanin: absence of pigment (Blue eyes = see the blood vessels)
Tumors
Cluster of cells that grow rapidly (abnormal)
Benign
grows slowly, not dangerous, maybe a little painful (very common)
Malignant
May break off the tumor and travel (metastasis)
Integument (Skin) system
Largest organ, heaviest (7% of body weight)
Protects against: UV, environment, bacteria
Regulates body temperature
Exretion
Sweat out the excess salt or alcohol
Glands in the female breast are modified sweat glands (Breast milk = modified sweat)
Vitamin D
Sun exposure = metabolism, growth of bones, in children
Thin skin
Hair, most of the body is covered
Thick skin
No hair, soles and palms
Sebum
Hair oil, from the sebaceous gland
Too much = acne
Water helps dilute this
Sweat glands (Specialized versions)
Ear: wax
Breast: milk
Meisner’s Touch receptors
Nerve endings in the hand
Deal with delicate touch
Palm and fingers have a lot
A lot in your face
Pacinian corpuscles
Pressure receptors: Vibration and deep pressure
Numerous in the sole of the feet
Used in learning to walk
abundant in the hand
Melanocycte
Melanin containing cells
We all have the same number of cells
Skin color: how much pigment you have/ white = less pigment not less melanocytes
Tattoos
Subcutaneous epidermis (fat layer) is penetrated Keeps the pigment there longer
Skin Cancer
Most common form of cancer (1/3 of all cancer)
98% is curable
3 forms of skin cancer
- Squamous cell cacerinoma
- Basil Cell
- Melanoma
Squamis cell carcerinoma
Cancer, flkay cell, epidermis
treatable
Doesnt not metastasize
Basil Cell
Base of the epidermis, Roundish, Doesnt break the base membrane
Treatable
Doesnt Metastasize
Melanonma
Least treatable
Melanocytes are cancerous
Cells divide very rapidly, they metastasize very quickly
Least common
ABCDE’s of Melanoma
A: Asymmetry (Not round circle) B: borders, not smooth are irregular C: colors, various colors D: diameter, eraser of a pencil (bigger might be melanoma E: evolving, ever changing and growing
Burns
Thermal: Excessive heat
Electrical: hot electrical wire, lightning
Chemical: strong acids and bases
Inhalation: breath in things that are dangerous
Friction Burns: rope burns
Radiation: explosions, atomic (radioactive)
1st degree burn
Only top layer of epidermis,
Sun burns
2nd degree burn
Through epidermis
Fluid rushes in, blisters form
3rd degree
Epidermis and demis is destroyed, nerves as well,
No sensation, painless
Full thickness burn
Require skin graphs
4th degree
All epi and dermis, down to deep tissue
Muscle, ligament and bones
Amputation is required