Lecture 3 10/14/24 Flashcards

1
Q

What are fungal nasal granulomas?

A

uncommon localized infection of the nasal mucosa resulting in granulomatous inflammation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What causes fungal nasal granuloma?

A

various mycotic and bacterial pathogens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the pathophysiology of fungal nasal granuloma?

A

-causative agent attracts macrophages to site
-macrophages induce tissue damage and granulomatous inflammation
-granuloma disrupts normal airflow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the clinical signs of fungal nasal granuloma?

A

-upper resp. noise/stertor
-dyspnea
-unilateral bloody or mucopurulent nasal discharge**
-disrupted nasal airflow**

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

How are fungal nasal granulomas diagnosed?

A

biopsy and culture/histopathology to identify hyphae/sporidium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the characteristics of sodium iodide treatment for fungal nasal granuloma?

A

-each treatment consists of one bottle of NaI going IV
-repeated every week until signs of iodism occur
-pretreat with dexamethasone for anaphylaxis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are the signs of iodism?

A

-flaky skin
-ropey nasal discharge
-alopecia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

How many NaI treatments does it typically take to develop iodism?

A

2 to 3 treatments

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is allergic rhinitis/enzootic nasal granuloma?

A

allergy against pollen or fungal spores

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What causes acute allergic rhinitis?

A

mast cells and IgE mediate inflammation in a type 1 hypersensitivity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What causes enzootic nasal granuloma?

A

macrophage-mediated inflammation and repeated mast cell damage induces granulomas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are the clinical signs of acute allergic rhinitis?

A

-sneezing
-nasal discharge
-pruritis
-dyspnea
-stertorous breathing
-inflamed mucosa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

In addition to the allergic rhinitis signs, what other clinical sign is seen in enzootic nasal granuloma?

A

multiple focal granulomas or plaques throughout the nasal cavity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Which animals are most likely to get allergic rhinitis/enzootic nasal granuloma?

A

-channel island breeds
-younger animals
-animals in the summer/in warm and moist environments

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

How is allergic rhinitis/enzootic nasal granuloma diagnosed?

A

-visualization of nasal cavity
-intradermal skin testing/allergen ID; valuable animals only

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the main treatment options for allergic rhinitis/enzootic nasal granuloma?

A

-dexamethasone
-flunixin meglumine

17
Q

What are the concerns surrounding dexamethasone use?

A

-will induce parturition in pregnant cows
-can cause immunosuppression with repeat doses

18
Q

What are the other potential treatments for allergic rhinitis/enzootic nasal granuloma?

A

-isofluprednisone
-topical corticosteroids
-antihistamines

19
Q

What is the pathophysiology of sinusitis?

A

dehorning opens the frontal sinus to debris and opportunistic infections

20
Q

What are the acute phase clinical signs of sinusitis?

A

-unilateral nasal discharge
-malaise
-fever
-stertor
-anorexia

21
Q

What are the chronic phase clinical signs of sinusitis?

A

-nasal discharge
-head tilt
-foul breath
-facial malformation
-exophthalmos

22
Q

How is sinusitis diagnosed?

A

-percussion of the sinuses
-observation of symmetry changes, nasal/ocular discharge

23
Q

How is sinusitis treated?

A

-drilling into sinuses and lavaging
-procaine penicillin G
-flunixin meglumine

24
Q

What are the best methods of dehorning?

A

-select for polled-ness when breeding
-dehorn at 2-6 weeks of age

25
Q

What are retropharyngeal abscesses?

A

abscesses arising from local trauma in the pharyngeal area

26
Q

What are the clinical signs of retropharyngeal abscesses?

A

-visible swelling beneath jaw/in throat latch
-inspiratory dyspnea
-extended neck
-ptyalism
-pain on swallowing
-regurg. of food through nostrils
-cough
-bloat

27
Q

What is the treatment for retropharyngeal abscesses?

A

-lance and drain while carefully avoiding jugular v., carotid a., and facial a.
-rumenostomy for temp. feeding
-antibiotics and NSAIDs

28
Q

What is necrotic laryngitis?

A

bacterial infection of the laryngeal mucosa

29
Q

Which bacterium is associated with necrotic laryngitis?

A

Fusobacterium necrophorum

30
Q

What is the pathophysiology of necrotic laryngitis?

A

-lesions arise from laryngeal irritation and trauma
-seen with long hauls, viral infections, and bawling/vocalization

31
Q

What are the clinical signs of necrotic laryngitis?

A

-nasal discharge
-foul breath
-dysphagia
-moist cough
-inspiratory dyspnea
-roaring

32
Q

How is necrotic laryngitis treated?

A

-any antibiotic
-flunixin NSAID
-tracheostomy in severe cases

33
Q

What is tracheal edema syndrome?

A

progressive, dramatic constriction of the trachea of feedlot cattle with an UNKNOWN etiology

34
Q

What is the typical signalment of cattle with tracheal edema syndrome?

A

-heavy cattle
-late in the feed period

35
Q

What is the acute presentation of tracheal edema syndrome?

A

-dyspnea
-open-mouth breathing
-death
-“honkers”

36
Q

How is tracheal edema syndrome treated?

A

-often not treated due to poor prognosis
-corticosteroids
-antibiotics
-NSAIDs
-heat abatement