Lecture 1: Autonomic Nervous System Flashcards
Peripheral Nervous system
-autonomic
-somatic
autonomic nervous system
-REGULATE activity of smooth and cardiac muscle
-autonomic tone
-sympathetic and parasympathetic
autonomic tone
-involuntary
-pathways work while we rest
somatic nervous system
-control skeletal muscles
Sympathetic nervous system
fight or flight
parasympathetic
rest and digest
ANS pathway
-2 neurons
-preganglionic neron to postganglionic neuron to target cell
Preganglionc Neuron
-CNS
-first neuron in ANS signal pathway
-projects to ganglia
Postganglionic Neuron
-Peripheral
-projects to target organ
Primary transmitter of ALL PREganglionic neurons
acetylcholine
transmitter in PSNS POSTganglionic neurons
acetylcholine
transmitter in most SNS POSTganglionic neurons
norepinephrine
Acetylcholine
-transmitter of PREganglionic neurons and PSNS POSTganglionic neurons
-also in sweat glands
Norepinephrine
-transmitter in most SNS POSTganglionic neurons
Epinephrine
adrenal medulla
dopamine
renal vasculature
PARASYMPATHETIC Preganglionic neurons
-long
-synapse with postganglionic neurons near organ
-release ACH to activate nicotinic receptors on postganglionic neurons
PARASYMPATHETIC Postganglionic Neurons
-SHORT
-synapse on target organ
-release ACH to activate receptors on target organ
SYMPATHETIC Preganglionic neurons
-SHORT
-synapse near spinal cord
-relase ACH to activate nicotinic receptors on postganglionic neurons
SYMPATHETIC POSTganglionic neurons
-LONG
-synapse on target organ
-release NOREPINEPHRINE to activate adrenergic receptors on target organs
Sweat gland postganglionic neurons
-release NOREPINEPHRINE for stress related release
-release ACH for THERMOREGULATION release
Adrenal Gland preganglionic neurons
-sympathetic
-do not synapse in ganglion
-synapse right on adrenal gland
-release ACH
-release EPINEPHRINE to circulation
Kidney
also affected by dopamine
exceptions to SNS ganglia
-sweat gland
-adrenal gland
-kidney
Neuron types
-cholinergic
-adrenergic
cholinergic neurons
-PARASYMPATHETIC
-ACH, muscarine, nicotine
adrenergic neurons
-norepinephrine
-epinephrine
Receptor agonists
-drug mimics neurotransmitters
-ACTIVATE
Drug mimics Acetylcholine
-cholinergic
-muscarinic AGONIST
-parasympathomimetic
Drug blocks acetylcholine
-ANTIcholinergic
-muscarinic ANTAgonist
-parasympathoLYTIC
receptor antagonists
-BLOCK neurotransmitters
drug mimics norepinephrine
-adrenergic
-adrenergic agonist
-sympathomimetic
drug blocks norepinephrine
-antiadrenergic
-adrenertic antagonist
-sympatholytic
