Allergic Rhinitis

Question 1

Allergic rhinitis

Answer 1

-inflammatory
-IgE mediated

Question 2

allergic rhinitis symptoms

Answer 2

-nasal congestion
-rhinorrhea
-sneezing and/or itching
-post nasal drip that leads to cough
-allergic salute (nasal crease)
-allergic conjuctivitis
-fatigue, depression, irritability

Question 3

Pathophysiology of allergic rhinitis

Answer 3

-sensitization and presentation of allergen fragments
-CD4->TH2->Bcell–>IgE binds to mast cell
-re-exposure causes mast cell to release some shit = sneezing itching runny nose
-TH2 and eosininophils = congestion and hyperreactivity

Question 4

snesitized mast cell releases

Answer 4

-histamine
-leukotrienes
-prostaglandins
-tryptase
-kinins

Question 5

how common is allergic rhinitis

Answer 5

-most common chronic disease in children
-must first be exposed to antigen
-allergic triad

Question 6

allergic triad

Answer 6

-atopic dermatitis
-asthma
-allergic rhinits

Question 7

most common allergens

Answer 7

-seasonal (grasess)
-perennial (mold/dust)
-episodic (animal dander)
-mixed

Question 8

nonallergic vs allergic

Answer 8

-airborne irritants
-adults
-chronic rhinorrea
-sneezing uncommon

Question 9

allergic rhinitis discharge color

Answer 9

clear

Question 10

classifications

Answer 10

-mild, mod, severe
-intermittent vs persistent
-seasonal vs perennial

Question 11

goals of therapy

Answer 11

0minimize symptoms and side effects
-maintain qol
-give it 2-4 weeks

Question 12

mild intermittent treatment

Answer 12

-oral antihistamine w or w/o decongestant
-intranasal antihistamine

Question 13

mod to severe intermittent treatment

Answer 13

-OAH +/- decongestant
-INA
-Leukotriene antagonist
-intranasal corticosteroid

Question 14

mild persistent treatment

Answer 14

-OAH +/- decongestant
-INA
-INCS

Question 15

mod to severe persistent

Answer 15

1. INCS
2. OAH +/- decongestant
3. LTRA

in order