52-53: medications in preg and lactation NOT DONE Flashcards
inc what in prenatal diet
-300-400 calories
-folate and folic acid
-calcium intake
-vitamin D
-protein
dec what in prenatal diet
-artificial sweeteners
-unpasteurized foods
-alcohol
-unwashed fruits and veggies
-herabl teas
-undercooked meat
-caffeine
Caffeine intake during pregnancy
-takes longer to be metabolized
-less than 200 mg/day
Benefits of prenatal supplements
-help w fetal development
-prevent fetal and maternal complications
Timing of prenatal supplements
-ideally start 3 months before conception
-folic acid at least one month before getting preg
Prenatal vitamins and minerals
-calcium
-iron
-iodine
-choline
-Vit A, B6, B12, C, D
-folic acid
Vaccine recommendations for pregnant women
-inactivated influenza
-Tdap during each pregnancy
-RSV weeks 32-36
-covid-19
Vaccines to AVOID in pregnant women
-HPV
-MMR
-LIVE influenza
-Varicella
-yellow fever
-typhoid fever
Fetal alcohol syndrome
-CNS abnormalities
-growth defects
-facial dysmorphia
Fetal alcohol syndrome birth defects
-growth deformities
-facial abnoramlities
-CNS impairment
-behavior disorders
-impaired intellectual development
Tobacco use during pregnancy
-preterm birth
-low birth weight
-birth defects
-sudden infant death syndrome
Marijuana use during pregnancy
-low birth weight
-brain development disruption
-decreased attention span
-behavioral problems
-marijuana use in child by 14
Opioid use during pregnancy
-maternal death
-poor fetal growth
-preterm birth
-still birth
-neonatal withdrawal
medication for substance abuse
-methadone
-buprenorphine
Neonatal Opioid Withdrawal Syndrome
-72 hours after birth
-tremors
-sleep problems
-reflexes
-seizures
-poor feeding
-shit and vomit
Neonatal opioid withdrawal syndrome treatment
-buprenorphine, morphine, methadone
-IV fluids
-higher calorie formula
Absorption in pregnancy
-slower GI
-inc extent of absorption
-dec rate of absorption
Distribution in pregnancy
-inc Vd of hydrophillic drugs
-dec protein binding
Metabolism in pregnancy
-inc CYP3A4 activity
-dec CYP2C19 activity
Excretion in pregnancy
-inc renal hepatic blood flow
-inc CrCl
Teratogen
-drug or environmental agent with potential to cause abnormal fetal growth and development
-hazardous medication and require special handling
Common teratogens
Short-term complications in pregnancy
-nausea
-heartburn
-constipation
-pain, fever, headache
-cough and cold
-UTI
Nausea and vomiting risk factors in pregnancy
-h/o motion sickness
-GERD
-high fat diet
-younger patients
Hyperemesis gravidarum
-severe formm of nausea and vomiting
-weight loss, electrolyte imbalances, dehydration
Nausea and vomiting treatment
1st nonpharmacologic
2nd pharmacologic
Non-pharmacologic treatment of vomiting
-avoid triggers
-drink throughout the day
-eat smaller, freq, dry meals
-eat dry toast or crackers before getting out of bed
-avoid spicy foods
-keep stomach from being empty
Pharmacological treatment
- Pyridoxine (Vit B6)
- Doxylamine and Pyridoxine
- Meclizine, Dimenhydrinate, diphenhydramine
- ondansetron, metoclopramide