lactation Flashcards

1
Q

what is the name of the first milk produced

A

colostrum

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2
Q

how long should women breast feed exclusively for

A

6 months

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3
Q

what are the health benefits of breast feeding to the baby

A
reduced infection
diabetes, asthma, eczema 
reduced lactose intolerance
improved psychomotor and intelligence
decreased obesity
reduced autoimmune disease
risk of autoimmune disease
reduced risk of sudden infant death syndrome
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4
Q

what are the health benefits of breast feeding to the mother

A

promotes recovery
promotes return of normal body weight
reduced risk of breast cancer and ovarian cancer
improves bones

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5
Q

what is lactational amenorrhoea

A

prolactin suppresses GnRH and so FSH and LH reduced

follicular growth, ovulation and menstruation reduced

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6
Q

describe the male breast/ breast at birth

A

lactiferous ducts without alveoli

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7
Q

describe the breast at puberty

A

oestrogen causes the ducts to proliferate and alveoli form at the ends of the branches
at each menstrual cycle the alveoli proliferate and may secrete

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8
Q

describe the breast changes during pregnancy

A

oestrogen, progesterone and prolactin causes the glandular portion of the breast to hypertrophy
alveoli acquire a lumen
ready by week 16

adipose tissue regresses to be replaced with glandular tissue

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9
Q

what are alveoli made from

A

modified sebaceous glands

they empty via lactiferous ducts that form lactiferous sinuses which open on to the areola

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10
Q

what cells contain receptors for oxytocin

A

myoepithelial cells

which surround the alveolus

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11
Q

what cells have receptors for prolactin

A

secretory alveoli cells

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12
Q

what 3 tissue types make up the breast

A

fibrous
glandular
adipose

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13
Q

what are the two components of lactation

A

milk production and let down aka milk production reflex

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14
Q

what initiates lactation after delivery

A

precipitous drop in progesterone and oestrogen after delivery

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15
Q

what hormone sustains milk production

A

each time mother nurses prolactin surges from nipple to hypothalamus

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16
Q

what hormone is produced when not nursing

A

prolactin inhibitory hormone which is produced by the hypothalamus

17
Q

what inhibits lactation during pregnancy

A

progesterone and oestrogen and human placental lactogen

hPL

18
Q

what is the role of prolactin in the suckling reflex

A

suckling inhibits release of dopamine (PIF) and prolactin is released in proportion to the strength and duration of suckling

19
Q

where is oxytocin produced

A

hypothalamus and carried to the posterior pituritary gland

causes let down

20
Q

what conditioned reflexes stimulates let down

A

baby crying

21
Q

what hormones inhibit oxytocin

A

catecholamines (stress)

22
Q

what type of secretion is milk

A

apocrine

23
Q

describe the synthesis of milk

A

milk fat moves in lipid droplets which are pinched off into the lumen

milk protein passes through the golgi apparatus and is exocytosed

24
Q

how long is colostrum produced for

A

a week

25
Q

when is mature milk produced

A

after 3 weeks

26
Q

describe the difference between colostrum and milk

A

milk has more calories, more carbs, more fat, more water soluble vitamins,

less protein, fewer fat soluble vitamins (A) less zinc and sodium, fewer antibodies

27
Q

how much milk is produced per day

A

800mls

28
Q

what is the main energy source in milk

A

fat

29
Q

what is the main carb found in milk

A

lactose

promotes growth of lactobacillus bifidus
provides galactose for myelin

30
Q

what proteins are found in milk

A

casein and lactalbumin

31
Q

what fat soluble vitamins are found in milk

A

A, D, E, K

32
Q

what water soluble vitamins are found in milk

A

B6 and 12, C, folate, niacin, riboflavin, thiamine

33
Q

how many sp of bacteria are in breast milk

A

600 sp

34
Q

what does colostrum contain

A

lots of proteins, antibodies and vitamins

35
Q

what is PIF the same as

A

dopamine

inhibits prolactin