L5 - Hematopoiesis

Question 1

primitive vs definitive hematopoiesis

Answer 1

Primitive hematopoiesis occurs in the yolk sac, and RBCs are nucleated and express embryonic globulin chains. Definitive hematopoiesis occurs in the liver and other lymphoid tissues, and RBCs are non-nucleated and express fetal or adult globulin chains.

Question 2

red vs yellow bone marrow

Answer 2

• Active bone marrow is red due to preponderance of RBCs.
• During aging, active bone marrow becomes yellow due to fat deposition. However, it retains the capacity to revert to red bone barrow if necessary.
• Red bone marrow concentrates at the epiphyses (ends of long bones)

Question 3

blood cell lineage

Answer 3