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M&I > L32 - Gram- Bacteria II > Flashcards

L32 - Gram- Bacteria II Flashcards

1
Q

yersinia pestis

microbiology

A

has a bipolar staining pattern (stains on either side but not in middle)

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2
Q

Yersinia pestis

virulence factors

A
  • LPS endotoxin
  • Coagulase
  • Fibrinolysin
  • LPS endotoxin
  • V and W antigens
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3
Q

Yersinia pestis

pathogenesis

A
  • Flea bites an infected rat
  • Flea bites a human
  • Bacteria travels to regional lymph nodes
  • Phagocytosed bacteria begins to express I antigen on capsule to prevent further phagocytosis
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4
Q

Yersinia pestis

clinical manifestations

A
  • Fever
  • Chills
  • Bubo - extremely tender lymph node with extensive swelling and possible necrosis
  • Pneumonic plague - dreaded complication of bubonic plague which can be spread human-to-human
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5
Q

Yersinia enterocolitica

pathogenesis

A
  • Organisms are ingested (undercooked pork)
  • Invasion of intestinal epithelium
    • Invasin
    • Attachment invasion locus
    • YadA
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6
Q

Yersinia enterocolitica

clinical manifestations

A
  • Fever
  • Diarrhea
  • Abdominal pain (mirroring that of appendicitis)
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7
Q

Pasteurella multocida

pathogenesis

A
  • Bacterial fimbriae cause adherence to mucosal membrane of animals
  • Bacteria transferred during an animal bite
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8
Q

Pasteurella multocida

clinical manifestations

A
  • Cellulitis
  • Lymphadenopathy
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9
Q

Francisella tularensis

microbiology

A
  • Possesses B-lactamase
  • Requires cysteine
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10
Q

Francisella tularensis

transmission

A
  • Tick or insect bite
  • Aerosols during skinning of animals (particularly rabbits)
  • No human-to-human transmission
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11
Q

Francisella tularensis

pathogenesis

A
  • Intracellular parasite of hepatocytes, macrophages, and endothelial cells
  • Prevents fusion of phagosome and lysosome
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12
Q

Francisella tularensis

clinical presentations

A
  • Presents similar to TB
  • Papular lesion at site of bite; followed by necrosis of the lesion (node and ulcer next to each other)
  • Pulse-temperature deficit (fever with decreased pulse)
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13
Q

Legionella pneumophila

microbiology

A
  • Distinct, branched-chain fatty acids in cell wall
  • Unencapsulated
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14
Q

Legionella pneumophila

pathogenesis

A
  • Bacteria grows in wet areas inside amoebas
  • Unaffected by chlorine
  • Bacteria enter humans via inhalation
  • Mip protein prevents fusion of phagosome with lysosome
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15
Q

Legionella pneumophila

clinical manifestations

A
  • Pneumonia
  • High fever
  • Diarrhea
  • Pontiac Fever
    • Caused by inhalation of only toxin
    • Results in fever only (no pneumonia)
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16
Q

has a bipolar staining pattern (stains on either side but not in middle)

A

yersinia pestis

microbiology

17
Q
  • LPS endotoxin
  • Coagulase
  • Fibrinolysin
  • LPS endotoxin
  • V and W antigens
A

Yersinia pestis

virulence factors

18
Q
  • Flea bites an infected rat
  • Flea bites a human
  • Bacteria travels to regional lymph nodes
  • Phagocytosed bacteria begins to express I antigen on capsule to prevent further phagocytosis
A

Yersinia pestis

pathogenesis

19
Q
  • Fever
  • Chills
  • Bubo - extremely tender lymph node with extensive swelling and possible necrosis
  • Pneumonic plague - dreaded complication of bubonic plague which can be spread human-to-human
A

Yersinia pestis

clinical manifestations

20
Q
  • Organisms are ingested (undercooked pork)
  • Invasion of intestinal epithelium
    • Invasin
    • Attachment invasion locus
    • YadA
A

Yersinia enterocolitica

pathogenesis

21
Q
  • Fever
  • Diarrhea
  • Abdominal pain (mirroring that of appendicitis)
A

Yersinia enterocolitica

clinical manifestations

22
Q
  • Bacterial fimbriae cause adherence to mucosal membrane of animals
  • Bacteria transferred during an animal bite
A

Pasteurella multocida

pathogenesis

23
Q
  • Cellulitis
  • Lymphadenopathy
A

Pasteurella multocida

clinical manifestations

24
Q
  • Possesses B-lactamase
  • Requires cysteine
A

Francisella tularensis

microbiology

25
Q
  • Tick or insect bite
  • Aerosols during skinning of animals (particularly rabbits)
  • No human-to-human transmission
A

Francisella tularensis

transmission

26
Q
  • Intracellular parasite of hepatocytes, macrophages, and endothelial cells
  • Prevents fusion of phagosome and lysosome
A

Francisella tularensis

pathogenesis

27
Q
  • Presents similar to TB
  • Papular lesion at site of bite; followed by necrosis of the lesion (node and ulcer next to each other)
  • Pulse-temperature deficit (fever with decreased pulse)
A

Francisella tularensis

clinical presentations

28
Q
  • Distinct, branched-chain fatty acids in cell wall
  • Unencapsulated
A

Legionella pneumophila

microbiology

29
Q
  • Bacteria grows in wet areas inside amoebas
  • Unaffected by chlorine
  • Bacteria enter humans via inhalation
  • Mip protein prevents fusion of phagosome with lysosome
A

Legionella pneumophila

pathogenesis

30
Q
  • Pneumonia
  • High fever
  • Diarrhea
  • Pontiac Fever
    • Caused by inhalation of only toxin
    • Results in fever only (no pneumonia)
A

Legionella pneumophila

clinical manifestations

M&I (32 decks)

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