L29 - Gram+ Bacteria II Flashcards
1
Q
Listeria monocytogenes
microbiology
A
- Gram+ (variable) bacilli (pleomorphic)
- Catalase+
- Oxidase-
- Tumbling motility (somersaulting motion due to 1-5 polar flagella)
- Incompletely hemolytic
- Non-sporulating
- Facultative anaerobe
- Can grow in refrigerators
2
Q
Listeria monocytogenes
colonization
A
- Present in uncooked foods (generally meats, dairy products)
- Enters through GI tract and waits for opening (increased pH, injury, another infection)
- Once in bloodstream, it migrates toward central nervous tissue
3
Q
Listeria monocytogenes
virulence
A
- Internalin interacts with E-cadherin to promote phagocytosis
- Listeriolysin O and phospholipases help the bacteria escape intracellular killing
- Passed between cells via filopods
- Act A - induces actin filament assembly
- Siderophores - takes iron from transferrin
4
Q
- Gram+ (variable) bacilli (pleomorphic)
- Catalase+
- Oxidase-
- Tumbling motility (somersaulting motion due to 1-5 polar flagella)
- Incompletely hemolytic
- Non-sporulating
- Facultative anaerobe
- Can grow in refrigerators
A
Listeria monocytogenes
microbiology
5
Q
- Present in uncooked foods (generally meats, dairy products)
- Enters through GI tract and waits for opening (increased pH, injury, another infection)
- Once in bloodstream, it migrates toward central nervous tissue
A
Listeria monocytogenes
colonization
6
Q
- Internalin interacts with E-cadherin to promote phagocytosis
- Listeriolysin O and phospholipases help the bacteria escape intracellular killing
- Passed between cells via filopods
- Act A - induces actin filament assembly
- Siderophores - takes iron from transferrin
A
Listeria monocytogenes
virulence
7
Q
Nocardia microbiology
A
- Weakly Gram+
- Branching filaments
- Aerobic
- Sometimes acid-fast
8
Q
Nocardia colonization
A
- Aerosol transmission (no human-to-human)
- Acquisition through respiratory tract, GI tract, or trauma
- Facultatively intracellular
- Tropism for cerebral tissue
9
Q
Nocardia
immune evasion
A
- Super-oxide dismutase - resistance against phagocytic killing
- Increased catalase - neutralizes phagosomal acidification
10
Q
- Weakly Gram+
- Branching filaments
- Aerobic
- Sometimes acid-fast
A
Nocardia microbiology
11
Q
- Aerosol transmission (no human-to-human)
- Acquisition through respiratory tract, GI tract, or trauma
- Facultatively intracellular
- Tropism for cerebral tissue
A
Nocardia colonization
12
Q
- Super-oxide dismutase - resistance against phagocytic killing
- Increased catalase - neutralizes phagosomal acidification
A
Nocardia
immune evasion
13
Q
Actinomyces
microbiology
A
- Gram+
- Non-sporulating
- Anaerobic and microaerophilic (won’t die in a little bit of oxygen)
- Large, rough, white colonies
14
Q
actinomyces
pathogenesis
A
Endogenous acquisition (part of normal flora, trauma brings it in)
15
Q
- Gram+
- Non-sporulating
- Anaerobic and microaerophilic (won’t die in a little bit of oxygen)
- Large, rough, white colonies
A
Actinomyces
microbiology
