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M&I > L34 - Gram- Bacteria IV > Flashcards

L34 - Gram- Bacteria IV Flashcards

1
Q

Vibrio cholerae

toxin

A
  • 6 subunits - 5B + 1A
    • B binds to ganglioside GM1
    • A activates adenylate cyclase
  • Increased cAMP
    • Blocks absorption of sodium and chloride
    • Promotes secretion of chloride and water
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2
Q

Vibrio cholerae

microbiology

A
  • Rapid, linear motion
  • Can switch between dormant and active states (for years)
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3
Q

enterotoxigenic Escherichia coli (ETEC)

A
  • Most common cause of traveler’s diarrhea
  • Spread via contaminated water
  • Toxins
    • LT - almost identical to cholera toxin
    • ST - stimulates cGMP, producing similar effects as cAMP
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4
Q

Enterohemorrhagic Escherichia coli (EHEC)

transmission

A
  • Food
    • Bovine origin
    • Vegetables contaminated during irrigation
  • Water
    • Drinking water
    • Swimming
  • Direct Human Contact
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5
Q

Enterohemorrhagic Escherichia coli (EHEC)

clinical presentation

A
  • Watery diarrhea that becomes bloody
  • Hemolytic uremia syndrome
    • Hemolysis
    • Kidney failure (possible lifetime dialysis)
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6
Q

types of E. coli

A

ETEC, EPEC, EIEC, EHEC

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7
Q

Shigella

pathogenesis

A
  • Damage and destruction of colon lining
  • Transmission via flies and human-to-human contact
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8
Q

Shigella

clinical presentation

A
  • Frequent passing of stools (5-7 times a day)
  • Blood and mucus in stools
  • Abdominal pain
  • fever
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9
Q
  • 6 subunits - 5B + 1A
    • B binds to ganglioside GM1
    • A activates adenylate cyclase
  • Increased cAMP
    • Blocks absorption of sodium and chloride
    • Promotes secretion of chloride and water
A

Vibrio cholerae

toxin

How well did you know this?
1
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10
Q
  • Rapid, linear motion
  • Can switch between dormant and active states (for years)
A

Vibrio cholerae

microbiology

How well did you know this?
1
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11
Q
  • Most common cause of traveler’s diarrhea
  • Spread via contaminated water
  • Toxins
    • LT - almost identical to cholera toxin
    • ST - stimulates cGMP, producing similar effects as cAMP
A

enterotoxigenic Escherichia coli (ETEC)

How well did you know this?
1
Not at all
2
3
4
5
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12
Q
  • Food
    • Bovine origin
    • Vegetables contaminated during irrigation
  • Water
    • Drinking water
    • Swimming
  • Direct Human Contact
A

Enterohemorrhagic Escherichia coli (EHEC)

transmission

How well did you know this?
1
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3
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13
Q
  • Watery diarrhea that becomes bloody
  • Hemolytic uremia syndrome
    • Hemolysis
    • Kidney failure (possible lifetime dialysis)
A

Enterohemorrhagic Escherichia coli (EHEC)

clinical presentation

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14
Q

ETEC, EPEC, EIEC, EHEC

A

types of E. coli

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15
Q
  • Damage and destruction of colon lining
  • Transmission via flies and human-to-human contact
A

Shigella

pathogenesis

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16
Q
  • Frequent passing of stools (5-7 times a day)
  • Blood and mucus in stools
  • Abdominal pain
  • fever
A

Shigella

clinical presentation

M&I (32 decks)

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