L23 (Part II) - B Flashcards
____ is the parasite known to be “brain eating” (primary amebic meningoencephalitis - PAM). It is associated with swimming in warm, non-chlorinated water.
N. fowleri
Which two stages are associated with N. fowleri?
1) Ameboid
2) Flagellated
How does N. fowleri cause PAM?
Ameobas enter nares, penetrate cribriform plate, cause meningioencephalitis
What are the three stages of the N. fowleri lifecycle?
1 - Cyst
2 - Ameboid trophozoite stage*
3 - Flagellate
True or False: The ameboid trophozoite stage of N. fowleri lifecycle is the INFECTIVE STAGE
True
_____: Process in N. fowleri in which trophozoites replicate via: binary fission, but nuclear membrane remains intact
Promitosis
_____: A temporary, non-feeding, flagellated stage of N. fowleri when stimulated by adverse environmental changes, such as: reduced food source. Revert back when conditions are favorable.
Trophozoites/trophozoite
____ of N. fowleri are environmentally resistant in order to increased chance of survival until better environmental conditions occur
Cysts
Symptoms of infection with N. fowleri?
1) Headache
2) Fever
3) Stiff neck
4) Seizures
5) Hallucinations
- Death in 5 days
Dx. N. fowleri?
1) CSF
2) Biopsy
3) PCR
4) Culture
5) Antigen detection
6) Visualize trophozoites (CSF/Tissue) or flagellated amoeba in CSF
True or False: Direct fluorescent can be used to see histopath features of N. fowleri
True
Acanthamoeba is more commonly associated with corneal infections (keratitis), particularly among ____ ____ users.
contact lens
In immune compromised persons, Acanthamoeba causes…
1)
2)
1) GAE
2) Disseminate infections
Although both the cysts and trophozoites of Acanthamoeba gain entry into the body, only the ___ are the infective forms
A. Cysts
B. Trophozoites
B. Trophozoites
True or False: Acanthamoeba cysts and trophozoites are found in tissue and can invade immune system
True
Which three conditions are apt to arise with infection by Acanthamoeba?
