Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Y4R6 - Pediatrics II 👶 > L1: Anemia - Intro > Flashcards

L1: Anemia - Intro Flashcards

1
Q

Formation of RBCs

  • Timing
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Formation of RBCs

  • Site
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Formation of RBCs

  • Stages
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Formation of RBCs

  • changes in Nucleus, Size, Hb
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Formation of RBCs

  • Factors Affecting erythropoiesis
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Factors Affecting erythropoiesis

  • Metals
A
  • Iron → Hb
  • Copper → Heme
  • Cobalt
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Factors Affecting erythropoiesis

  • Vitamins
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Factors Affecting erythropoiesis

  • Hormones
A
  • Thyroid gland → T3, T4
  • Anterior pituitary gland → GH
  • Adrenal gland → CTS
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Factors Affecting erythropoiesis

  • Proteins
A

They are essential for formation of the globin part of Hb

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Factors Affecting erythropoiesis

  • EPO
A

A protein substance secreted by the kidney & stimulates erythropoiesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Size of Hb

A

1/3 of RBC mass

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Structure of Hb

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Types of Hb

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Types of Hb

  • Hb A
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Types of Hb

  • Hb F
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Types of Hb

  • Hb A2
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Fate of Hb

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Life span of RBCs

A

120 Days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Def of Anemia

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Types of Anemia

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Most common anemia in Egypt

A

Iron deficiency anemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Most common acute hemolytic anemia in Egypt

A

G6PD deficiency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q
  • Most common chronic)hemoly tic anemia in Egypt
  • Only microcytic hypochromic chronic hemolytic anemia
A

Thalassemia

24
Q

CP of Anemia

25
Q

Causes of Anemia

26
Q

Causes of Microcytic Anemia

27
Q

Causes of Microcytic Anemia

  • Defective globin chain
A
  • Thalassemias
28
Q

Causes of Microcytic Anemia

  • Defective heme synthesis
A
  • Anemia of chronic disease
  • Iron deficiency (late)
  • Lead poisoning
29
Q

Causes of Normocytic Anemia

30
Q

Causes of Normocytic Anemia

  • Nonhemolytic (low reticulocyte index)
A
  • Iron deficiency (early)
  • Anemia of chronic disease
  • Aplastic anemia
  • Chronic kidney disease
31
Q

Causes of Normocytic Anemia

  • Hemolytic (high reticulocyte index)
32
Q

Causes of Normocytic Anemia

  • Intrinsic Hemolytic
33
Q

Intrinsic Hemolytic Causes of Normocytic Anemia

  • Membrane Defects
A
  • Hereditary spherocytosis
  • Paroxysmal nocturnal hemoglobinuria
34
Q

Intrinsic Hemolytic Causes of Normocytic Anemia

  • Enzyme Deficiencies
A
  • G6PD deficiency
  • Pyruvate kinase deficiency
35
Q

Intrinsic Hemolytic Causes of Normocytic Anemia

  • Hemoglobinopathies
A
  • Sickle cell anemia
  • HbC disease
36
Q

Extrinsic Hemolytic Causes of Normocytic Anemia

A
  • Autoimmune
  • Microangiopathic
  • Macroangiopathic
  • Infections
37
Q

Causes of Macrocytic Anemia

38
Q

Causes of Macrocytic Anemia

  • Megaloblastic
39
Q

Causes of Macrocytic Anemia

  • Non-Megaloblastic
40
Q

INVx for Anemia

A
  • CBC (PBE)
  • BM Aspiration
  • Cut-off level of Hb & Hct for anemia
  • Coomb’s Test
  • Reticulocytic count
41
Q

INVx for Anemia

  • CBC (PBE)
46
Q

INVx for Anemia

  • BM Aspiration
47
Q

INVx for Anemia

  • Cut-off level of Hb & Hct for anemia
48
Q

INVx for Anemia

  • Coomb’s Test
49
Q

Technique of Coomb’s Test

50
Q

Interpretation of Coomb’s Test

A

Presence of antibodies against RBCs → Immune anemia

51
Q

INVx for Anemia

  • Reticulocytic Count
52
Q

Reticulocytic Count in Anemia

  • Technique
A
  • Measuring the percentage of all RBCs that are reticulocytes
53
Q

Reticulocytic Count in Anemia

  • Importance
A
  • It is an index for bone marrow activity
54
Q

Reticulocytic Count in Anemia

  • Normal Value
A

1 - 2 % of RBCs count

55
Q

Reticulocytic Count in Anemia

  • Decreased Result
A
  • Anemia due to decreased production of red cells
  • It is < 3% and frequently < 1.5%
56
Q

Reticulocytic Count in Anemia

  • Elevated Result
A

Hyperactive bone marrow (Increased Erythropoiesis)

  • Hemolysis
  • Blood loss
  • Anemia under treatment
  • Recovery from BM suppression
57
Q

Reticulocytic Count in Anemia

  • Reticulocyte Index

Y4R6 - Pediatrics II 👶 (50 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions