Infection - Tetanus Flashcards
Causative Organism of Tetanus
Clostridium tetani
Characters of Clostridium tetani
- Gram +ve bacilli
- Motile
- Obligate anaerobic
- Spore forming
Clostridium tetani
- Natural habitat
- Spores
- Vegetative Forms
Mode of Infection by Tetanus
IP of Tetanus
2 - 14 days (up to 1 month)
Pathogenesis of Tetanus
Pathogenesis of Tetanus
- Tetanospasmin
Pathogenesis of Tetanus
- Tetanolysin
CP of Tetanus
CP of Tetanus
- Clinical Form
- Generalized tetanus
- Neonatal tetanus
- Localized tetanus
CP of Tetanus
- Generalized Tetanus
Generalized Tetanus
- fever
- Fever โฅ 40ยฐC due to sustained metabolic activity by the muscles.
Generalized Tetanus
- Early symptoms
- Headache, restlessness and irritability are often the early symptoms
Generalized Tetanus
- Pain
Patient remains conscious and experience severe pain
- As tetanus doesnโt affect cortical or sensory functions and the
Generalized Tetanus
- Ms Spasm
Generalized Tetanus
- Tetanic Seizures
Tetanic Seizures
- PPT By
- Composed Of
- Duration
- Complications
Perosns Suspectible to Neonatal Tetanus
Infants of inadequately immunized mother
* After unsterile management of umbilical stump
Neonatal Tetanus
- Incidence
Accounts for 500,000 infant deaths/year
Neonatal Tetanus
- Timing
3 - 12 days after birth
Neonatal Tetanus
- CP
Localized Tetanus
Site of Localized Tetanus
- Painful spasm of muscles adjacent to wound sites
Fate of Localized Tetanus
It may precede generalized tetanus
Example of Localized Tetanus
Cephalic Tetanus
* Localized tetanus involving bulbar muscles
* Occurs with contamination of head wounds
Dx of Localized Tetanus
Dx of Localized Tetanus
- Clinically
- Unimmunized patient + trauma + trismus, muscle rigidity + clear sensorium
Dx of Localized Tetanus
- Labs
Complications of Tetanus
Prevention of Tetanus
Prevention of Tetanus
- universal
โฆ
Prevention of Tetanus
- active
- Given at discharge to prevent recurrences
- Tetanus disease doesnโt produce protective neutralizing antibodies
Prevention of Tetanus
- Post-Traumatic Measures
TTT of Tetanus
TTT of Tetanus
- Eradication of C.Tetani
TTT of Tetanus
- Neutralization of Tetanus Toxins
TTT of Tetanus
- Supportive
Prognosis of Tetanus
Prognosis of Tetanus
- tetanic Paralysis
Prognosis of Tetanus
- death
Prognosis of Tetanus
- Favourable Outcomes
- Long incubation
- Localized disease
- Absence of fever