Infection - Tetanus Flashcards

1
Q

Causative Organism of Tetanus

A

Clostridium tetani

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2
Q

Characters of Clostridium tetani

A
  • Gram +ve bacilli
  • Motile
  • Obligate anaerobic
  • Spore forming
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3
Q

Clostridium tetani

  • Natural habitat
  • Spores
  • Vegetative Forms
A
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4
Q

Mode of Infection by Tetanus

A
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5
Q

IP of Tetanus

A

2 - 14 days (up to 1 month)

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6
Q

Pathogenesis of Tetanus

A
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7
Q

Pathogenesis of Tetanus

  • Tetanospasmin
A
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8
Q

Pathogenesis of Tetanus

  • Tetanolysin
A
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9
Q

CP of Tetanus

A
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10
Q

CP of Tetanus

  • Clinical Form
A
  1. Generalized tetanus
  2. Neonatal tetanus
  3. Localized tetanus
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11
Q

CP of Tetanus

  • Generalized Tetanus
A
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12
Q

Generalized Tetanus

  • fever
A
  • Fever โ‰ฅ 40ยฐC due to sustained metabolic activity by the muscles.
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13
Q

Generalized Tetanus

  • Early symptoms
A
  • Headache, restlessness and irritability are often the early symptoms
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14
Q

Generalized Tetanus

  • Pain
A

Patient remains conscious and experience severe pain
- As tetanus doesnโ€™t affect cortical or sensory functions and the

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15
Q

Generalized Tetanus

  • Ms Spasm
A
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16
Q

Generalized Tetanus

  • Tetanic Seizures
A
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17
Q

Tetanic Seizures

  • PPT By
  • Composed Of
  • Duration
  • Complications
18
Q

Perosns Suspectible to Neonatal Tetanus

A

Infants of inadequately immunized mother
* After unsterile management of umbilical stump

19
Q

Neonatal Tetanus

  • Incidence
A

Accounts for 500,000 infant deaths/year

20
Q

Neonatal Tetanus

  • Timing
A

3 - 12 days after birth

21
Q

Neonatal Tetanus

  • CP
22
Q

Localized Tetanus

23
Q

Site of Localized Tetanus

A
  • Painful spasm of muscles adjacent to wound sites
24
Q

Fate of Localized Tetanus

A

It may precede generalized tetanus

25
Q

Example of Localized Tetanus

A

Cephalic Tetanus
* Localized tetanus involving bulbar muscles
* Occurs with contamination of head wounds

26
Q

Dx of Localized Tetanus

27
Q

Dx of Localized Tetanus

  • Clinically
A
  • Unimmunized patient + trauma + trismus, muscle rigidity + clear sensorium
28
Q

Dx of Localized Tetanus

  • Labs
29
Q

Complications of Tetanus

30
Q

Prevention of Tetanus

31
Q

Prevention of Tetanus

  • universal
32
Q

Prevention of Tetanus

  • active
A
  • Given at discharge to prevent recurrences
  • Tetanus disease doesnโ€™t produce protective neutralizing antibodies
33
Q

Prevention of Tetanus

  • Post-Traumatic Measures
34
Q

TTT of Tetanus

35
Q

TTT of Tetanus

  • Eradication of C.Tetani
36
Q

TTT of Tetanus

  • Neutralization of Tetanus Toxins
37
Q

TTT of Tetanus

  • Supportive
38
Q

Prognosis of Tetanus

39
Q

Prognosis of Tetanus

  • tetanic Paralysis
40
Q

Prognosis of Tetanus

  • death
41
Q

Prognosis of Tetanus

  • Favourable Outcomes
A
  • Long incubation
  • Localized disease
  • Absence of fever