Infection - Diphtheria

Question 1

Causative Organism of Diphtheria

Answer 1

Corynebacterium diphtheria (only in humans)

Question 2

Characters of Corynebacterium diphtheria

Answer 2

• Gram +ve bacilli
• Non-capsulated
• Aerobic
• Non-spore-forming

Question 3

Types of Corynebacterium diphtheria

Answer 3

• Mitis
• Belfanti
• Gravis
• Intermedius

Question 4

Mode of Infection by Diphtheria

Answer 4

• Direct droplet
• Direct contact

Question 5

IP for Diphtheria

Answer 5

• 2 - 4 days

Question 6

Infectivity Period for Diphtheria

Answer 6

• No therapy: 4 weeks
• Therapy: 4 days

Question 7

Pathogenesis of Diphtheria

Question 8

Pathogenesis of Diphtheria

• Local Effects

Question 9

Pathogenesis of Diphtheria

• Systemic Effects

Question 10

CP of Diphtheria

Question 11

CP of Diphtheria

• Factors Contributing to CP

Answer 11

• Anatomic site of infection
• Immune status.
• Toxin production

Question 12

CP of Diphtheria

• Sites of Infection

Question 13

Respiratory Diphtheria

Question 14

Respiratory Diphtheria

• Tonsillar / Pharyngeal

Question 15

Respiratory Diphtheria

• Laryngeal

Question 16

Laryngeal Diphtheria

• Significance
• Cause
• CP
• Laryngoscopy

Question 17

Respiratory Diphtheria

• Nasal

Question 18

Cutaneous Diphtheria

Question 19

Site of Cutaneous Diphtheria

Answer 19

Extremities > Trunk & head

Question 20

Characters of Cutaneous Diphtheria

Answer 20

• Ecthymic non-healing ulcer with gray brown membrane

Question 21

Complications of Cutaneous Diphtheria

Answer 21

Toxic complications may occur in Minor Cases

Question 22

Other sites of Diphtheria

Question 23

Toxic Complications of Diphtheria

Question 24

Toxic Complications of Diphtheria

• Toxic Cardiopathy

Question 25

Toxic Complications of **Diphtheria** - Toxic Neuropathy

Question 26

INVx for **Diphtheria**

Question 27

Prevention of **Diphtheria**

Question 28

Prevention of **Diphtheria** - Active Immunization

Question 29

Prevention of **Diphtheria** - Passive Immunization

Question 30

TTT of **Diphtheria**

Question 31

TTT of **Diphtheria** - Supportive

Answer 31

As scheme

Question 32

TTT of **Diphtheria** - Antitoxin

Question 33

TTT of **Diphtheria** - Antibiotics

Answer 33

- To halt toxin production, treat localized infection, prevent transmission - Erythromycin or penicillin G for 14 days

Question 34

TTT of **Diphtheria** - Control Measures

Question 35

Control Measures of **Diphtheria** - Case Contacts

Question 36

Control Measures of **Diphtheria** - Asymptomatic Carriers