jan 19 Flashcards

1
Q

clinical features of serum-sickness-like reaction

A

fever
skin rash
polyarthralgia

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2
Q

what causes a serum-sickness-like reaction?

A

type III hypersensitivity reaction (can be in response to drugs such as penicillin)

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3
Q

which drugs may cause a serum-sickness-like reaction?

A

beta lactams and TMP-SMX

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4
Q

treatment of serum-sickness-like reaction?

A
  • remove offending agent
  • supportive care
  • if severe: steroids or plasmapheresis
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5
Q

should you use a CT with or without contrast in after an unprovoked first time seizure?

A

WITHOUT - more helpful in identifying intracranial hemorrhage and faster

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6
Q

what should you give to reverse warfarin induced bleeding?

A

vitamin K and prothrombin complex concentrate (contains vitamin K dependent clotting factors)

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7
Q

which type of cardiac hypertrophy is seen with acromegaly?

A

concentric hypertrophy

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8
Q

when may a baby start having pain crises in sickle cell disease?

A

usually not until about 6 months when the HbA increases

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9
Q

what should you give a patient with the reccurrence of anaphylactic symptoms after initial resolution?

A

IM epineprhine again

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10
Q

clinical features of preseptal cellulitis?

A
  • eyelid erythema and swelling

- chemosis

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11
Q

treatment of preseptal cellulitis?

A

oral antibiotics

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12
Q

clinical features of orbital cellulitis?

A
  • eyelid erythema and swelling, chemosis

- PLUS pain with extraocular movements, proptosis and or opthalmoplegia with diplopia

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13
Q

treatment of orbital cellulitis?

A

IV antibioitics +- surgery

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14
Q

treatment of papulopustular rosacea?

A

topical metronidazole

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15
Q

adverse effects of methimazole?

A
  • agranulocytosis

- 1st trimester teratogen, cholestasis

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16
Q

adverse effects of PTU?

A
  • agranulocytosis

- hepatic failure, ANCA-associated vasculitis

17
Q

which lung disease is associated with CREST syndrome?

A

pulmonary arterial hypertension

18
Q

lung biopsy findings of pulmonary arterial hypertension?

A

arterial intimal hyperplasia

19
Q

what is postthrombotic syndrome?

A

-chronic venous insufficiency following acute DVT that usually arises within 2 years of a DVT