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OBS and GYN > jan 18 > Flashcards

jan 18 Flashcards

1
Q

which type of lung cancer is assocaited with increased PTHrP?

A

squamous cell carcinoma of the lung

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2
Q

which enzyme is reduced in acute intermittent porphyria?

A

porphobilinogen deaminase

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3
Q

inheritance of AIP?

A

AD with low penetrance

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4
Q

manifestations of AIP?

A
  • abdominal pain
  • peripheral neuropathy mostly in upper extremities
  • autonomic dysfunction
  • neuropsychiatric dysfunction
  • red-tinged urine that oxidizes with light/air exposure
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5
Q

what are some exacerbating factors of AIP?

A
  • Medications (CYP450 inducers)
  • Psychological stress
  • Alcohol, tobacco
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6
Q

lab findings in AIP?

A
  • elevated serum & urinary PBG, ALA, porphryns

- hyponatremia, elevated transaminases

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7
Q

management of AIP?

A

glucose and hemin

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8
Q

why does hyponatremia occur in an AIP attack?

A

from SIADH

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9
Q

path of alport syndrome?

A

mutation of type IV collagen

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10
Q

clinical findings of alport syndrome?

A
  • nephropathy - hematuria, progressive renal insufficiency, proteinuria, hypertension
  • bilateral sensineural hearing loss
  • anterior lenticonus
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11
Q

renal biopsy findings of alport syndrome?

A

longitudinal splitting of GBM

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12
Q

inheritance of alport syndrome

A

X-linked

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13
Q

treatment of RSV bronchiolitis?

A

-supportive care

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14
Q

which infants with RSV bronchiolitis require palivuzimab?

A
  • <29 weeks gestation
  • chronic lung disease of prematurity
  • significant congenital heart diseaes
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15
Q

diagnosis of ALL?

A

bone marrow biopsy

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16
Q

which muscles does the suprascapular nerve supply?

A

supraspinatous and infraspinatous

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17
Q

presentation of suprascapular nerve injury?

A

pain

-weakness on abduction adn external rotation of shoulder

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18
Q

most common cause of lobar intracranial hemorrhage?

A

cerebral amyloid angiopathy

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19
Q

what causes bacillary angiomatosis?

A

Bartonella- gram - bacillus

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20
Q

treatment of bacillary angiomatosis?

A

oral erythromycin

21
Q

which cancer is associated with 9:22 translocation?

A

chronic myeloid leukemia

22
Q

path of idiopathic transverse myelitis?

A
  • immune mediated destruction of spinal cord

- often post-infectious (molecular mimicry)

23
Q

idiopathic transverse myolitis often follows…

A

an infection

24
Q

diagnosis of idiopathic transverse myelitis?

A

MRI: no compression lesion - T2 hyperintensity
LP: increased WBCs, increased IgG

25
treatment of idiopathic transverse myelitis?
- high dose IV glucocorticoids | - plasmapheresis
26
what aortic valve area measurement indicates severe aortic stenosis?
<1cm
27
treatment of bartonella angiomatosis?
-doxycycline or erythromycin
28
Management of uncomplicated spontaneous pneumomediastinum?
- rest - analgesics - avoidance of valsava maneuvers
29
adverse effect of hydroxychloroquine?
retinopathy
30
treatment of juvenile idiopathic arthritis?
NSAIDS
31
Management of EHEC?
supportive
32
presentation of carbon monoxide poisoning?
-headache, confusion, malaise, dizziness, nausea | Severe: seizure, syncope, coma, MI, arythmias
33
renal complications of long term analgesic use?
- chronic tubulointerstitial nephritis | - hematuria due to papillary necrosis
34
patients with hypothyroid are at increased risk for which bone disorder?
slipped capital femoral epiphysis
35
treatment of slipped capital femoral epiphysis?
surgical screw fixation
36
Dementia with executive function loss and neurologic findings is likely...
vascular dementia
37
hep B is a risk factor for which nephrotic syndrome?
membranous nephropathy
38
which medication can be given to children with enuresis?
desmopressin
39
what will nerve conduction studies show with GBS?
evidence of demyelinization (decreased motor nerve conductance)
40
is sensation effected in GBS?
no - although parasthesias may be present
41
CSF findings of GBS?
increased protein, normal leukocytes
42
presentation of ethylene glycol poisoning?
- flank pain - hematuria, oliguria - CN palsies, tetany
43
lab findings in ethylene glycol poisoning?
- high osmolar gap - high anion gap metabolic acidosis - calcium oxalate crystals in urine
44
treatment of ethylene glycol poisoning?
fomepizole
45
presentation of methanol ingestion?
- blurred vision - central scotoma - affarent pupillary defect - altered mentation
46
what causes a dermatofibroma?
benign fibroblast proliferation that may occur after trauma or insect bites
47
appearance of a dermatofibroma?
discrete, firm, hyperpigmented nodules <1cm in diameter | -may have dimpling when pinched
48
where in the brain do neoplastic cells commonly lodge?
at the grey-white matter junction

OBS and GYN (42 decks)

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