Introduction to Genetic Variation

Question 1

What are SNPs

Answer 1

Single nucleotide polymorphisms

Question 2

What is linkage disequilibrium?

Answer 2

Two alleles close to each other are not necessarily independent; sometimes the first one can tell you what the second one is/could be

Question 3

What is the genetic variation that leads to Huntington’s disease?

Answer 3

In gene at HD locus, >40 CAG repeats leads to an aggregate huntingtin protein

Question 4

What are the assumptions that must be made for hardy Weinberg equilibrium?

Answer 4

Random mating
Large population
No selection
No mutation
No migration