Amino acid metabolism Flashcards
1
Q
Which cycle is urea produced in?
A
Ornithine cycle
2
Q
How is creatinine produced?
A
Creatine phosphate breakdown in the liver
3
Q
How is uric acid produced?
A
DNA + RNA breakdown
4
Q
What occurs if NH3 cannot be converted to urea?
A
hyperammonaemia
5
Q
How are cellular proteins broken down?
A
Through the ubiquitin system
6
Q
What are the ketogenic AA
A
leucine and lysine, can only be degraded to acetylCoA
7
Q
What are the glucogenic AA
A
Phe, tyr
8
Q
What enzyme converts glutamine to glutamate?
A
Gluatminase, uses H2O produces NH3
9
Q
What does glutaminase do?
A
Converts glutamine to glutamate using water and producing NH3
10
Q
What enzyme converts glutamate to glutamine
A
Glutamine synthase, using ATP and NH3