Intro To AMP

Question 1

Pathology can be defined as the science that deals with the _______ and the _______

Answer 1

study of diseases

body’s response to diseases

Question 2

Pathos(_____ ), logos( ______)

Answer 2

suffering

study

Question 3

Pathology is a bridging discipline between _______ and _______

Answer 3

basic medicine and clinical
practice

Question 4

Cellular pathology/_____/ ______ is devoted to the study of ____________

It’s divided into ____ and ____

Answer 4

morbid anatomy; histopathology

structural and functional changes that underlie diseases.

General pathology and systemic pathology

Question 5

general pathology deals with the _____________________

Systemic pathology which examines ____________

Answer 5

basic reaction of the cells and tissues to abnormal stimuli that underlie disease

specific response of specialized organs and tissue to more or less well defined stimuli

Question 6

There are four disease processes that form the core of pathology

________
_________
_________
___________

Answer 6

etiology

Pathogenesis

Morphology

Clinical syndromes

Question 7

A medical pathologist is involved in chief complaint history and treatment.
T/F

Answer 7

F

Not involved in those

Question 8

Examples of histochemical technique

•Perls’s Reaction for detection of _____
• Von Kossa technique for _____
• Sudan black technique for _____
• Congo Red for _____
• PAS/PASD reaction for ______

Answer 8

Ferric ions

calcium

Lipids

amyloid

Carbohydrates

Question 9

PAS = _______

Answer 9

Periodic Acid Schiff

Question 10

WHAT IS H&E?
• The _______ and ______ Stain

Answer 10

Haematoxylin and Eosin

Question 11

Most commonly used fixative is ____% buffered ________ or ______

• Others
•______ solution for testis small biopsies will also decalcify
•______ contains alcohol for rapid processing. Dissolves fat good for
identifying lymph node
• _____ for lymphoid tissues

Answer 11

10; formal saline

Formalin

Boiun’s

Carnoy’s

B-5

Question 12

PROCESSING OF TISSUE
•________
• _______

Answer 12

FFPE

FROZEN SECTION

Question 13

_______________ (FFPE)

Answer 13

Formalin Fixed Paraffin Embedded

Question 14

Tissue constituent ; stain ; Disease

(1) Mucin
(2) Fibrin
(3)Amyloid
(4) Helicobacter pylori
(5)Haemosiderin,iron
(6) Connective tissue fibers

Answer 14

Mucicamine; Mucinous Adenocarcinoma

Reticulin stain; Necrotizing lesion in glomerulonephritis

Congo red ; Amyloidosis

Modified Giemsa stain; Chronic gastritis

Perl’s Prussian blue; Heamochromatosis

Masson’s trichome/Sirius Red; Liver cirrhosis

Question 15

Tissue constituent ; stain ; Disease

Mucin

Answer 15

Mucicamine

Mucinous Adenocarcinoma

Question 16

Tissue constituent ; stain ; Disease

Fibrin

Answer 16

Reticulin stain

Necrotizing lesion in glomerulonephritis

Question 17

Tissue constituent ; stain ; Disease

Amyloid

Answer 17

Congo red

Amyloidosis

Question 18

Tissue constituent ; stain ; Disease

Helicobacter pylori

Answer 18

Modified Giemsa stain

Chronic gastritis

Question 19

Tissue constituent ; stain ; Disease

Haemosiderin,iron

Answer 19

Perl’s Prussian blue

Heamochromatosis

Question 20

Tissue constituent ; stain ; Disease

Connective tissue fibers

Answer 20

Masson’s trichome/Sirius Red

Liver cirrhosis

Question 21

Steps in Paraffin embedded sections
1. Tissue taken from patients are first taken through ____________/__________

2. Processing in ___________. The tissue processing goes through four basic steps: _________,________,________
3. Embedded in ________ using embedding __________ to make ________
4. Microtomy-sections of this are ______ using __________,
5. Staining- sections cut are placed on __________ and stained with ____________________ stain

Answer 21

tissue fixation/preservation.

automatic tissue processor

dehydration, clearing, infiltration

paraffin wax ; center/station; tissue blocks

cut; microtome

glass slide; routine haematoxylin and eosin

Question 22

Steps in Paraffin embedded sections
1. tissue _______/_______
2. _________
3. _________
4. ___________
5. ——————-

Answer 22

fixation/preservation.

Processing

Embedding

Microtomy

Staining