Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

House AMP > Infective Endocarditis > Flashcards

Infective Endocarditis Flashcards

1
Q

Infective Endocarditis

This is an _______, _______ disease of the heart

Characterized by ___________ of the _______ or the _______ by microbiological agents with the formation of ______,______ ———- laden with microbiologic agents

A

infectious; inflammatory

colonization or invasion

heart valves ; mural endothelium

bulky, friable vegetations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Infective Endocarditis

May also affect the _____,_________ and other sites

A

aorta, aneurysmal vessels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Infective Endocarditis

There are 2 clinical subtypes
- _____
- __________

A

Acute

Subacute

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Infective Endocarditis

There are 2 clinical subtypes

In both cases, the organism affects the _______ causing _________ (called ______)

A

tissue

thrombus formation

vegetations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Infective Endocarditis

-Acute: a destructive infection on a previously (normal or damaged?) valve. The organisms are (mildly or highly?) virulent (eg ______).

Death occurs in _____% of cases

A

normal

highly; staph aureus

50

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Infective Endocarditis

-Subacute: this is common in previously (normal or damaged?) heart.

Causative organisms are (more or less?) virulent (eg ________).

It pursues a ______ course and patient recovers after _____________

A

damaged

Less

S.viridans

protracted; appropriate antibiotic therapy.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

PATHOGENESIS of infective endocarditis

1) Predisposing cardiac conditions

-________ heart disease
-________ heart disease
-___________ disease
- ___________________________ stenosis

A

Rheumatic

Congenital

Myxomatous mitral

Degenerative calcific valvular

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

PATHOGENESIS of infective endocarditis

2) Systemic conditions
- ______aenia
-__________ states (eg HIV)
-____________
- Chronic __________
- indwelling ________ (intracardiac/intravascular)
-____________ (injection)

A

Neutrop

Immunodeficiency

Diabetes Mellitus

alcoholism; catheters

Drug abusers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

PATHOGENESIS of infective endocarditis

Implicated organisms include,
Bacteria-_____,_____,_____,______

-Gram ____.organisms (_______)
Viruses
fungi

A

S.viridans, S.faecalis
-Staph
-S.pneumoniae

neg; E.coli

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

MORPHOLOGY of infective endocarditis

•______,______ vegetations on heart valves

•___________ of the valves

•Organization and ______

A

Friable , bulky

Ring abscess

fibrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

CLINICAL COURSE of infective endocarditis
Usually (specific or non-specific?)

Fever, malaise, loss of weight, _____ haemorrhage, _____ haemorrhage

A

non-specific

petechieal

subungal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

CLINICAL COURSE of infective endocarditis

___________- embolism of the central arteries of the ______ may cause ____ shaped haemorrhagic spot with a _______

A

Roth’s spot

retina; canoe

pale centre

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

COMPLICATIONS of infective endocarditis : CARDIAC

______ insufficiency with ________

————— abscess with perforation

A

Valvular; cardiac failure

Myocardial ring

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

COMPLICATIONS of infective endocarditis : CARDIAC

________ pericarditis (as opposed to the ‘__________’ seen in rheumatic heart disease.

_________ of artificial valves

A

Suppurative

bread and butter

Dehiscence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

COMPLICATIONS of infective endocarditis : RENAL

•________ ———-

•(Focal or diffuse?) glomerulonephritis leading to ________ and _______

A

Embolic infarcts

Focal

nephrotic syndrome and renal failure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

COMPLICATIONS of infective endocarditis : RENAL

•Diffuse glomerulonephritis due to _________________

•Multiple ______ with ______ bacteria

A

Ag-Ab complex formation

renal Abscess

staphylococci

17
Q

NON-BACTERIAL THROMBOTIC ENDOCARDITIS
(NBTE)
Also called _________

A

Marantic Endocarditis

18
Q

NON-BACTERIAL THROMBOTIC ENDOCARDITIS
(NBTE)

Are ______ seen in patients with _______

A

Vegetations

debilitating illness

19
Q

NON-BACTERIAL THROMBOTIC ENDOCARDITIS
(NBTE)

Associated with _______ ———carcinoma

Also associated with ________ leukaemia

A

mucinous adeno

promyelocytic

20
Q

mucinous adenocarcinoma: Mucin has a ______ effect

promyelocytic leukaemia: ________ state

A

pro-coagulant

Hyperestrogenic

21
Q

NBTE : MORPHOLOGY

Deposition of (small or large?) (sterile or non-sterile?) _____ masses in _____ that are (normal or abnormal?) and vegetations do not contain _________

A

Small

Sterile

Fibrin; valve leaflets

Normal; micro-organisms

22
Q

NBTE: MORPHOLOGY

Mostly occurs in ______ and _____ valves

A

aortic and mitral

23
Q

NBTE May cause embolism

T/F

24
Q

Infective endocarditis in pre-existing NBTE is usual

T/F

25
LIEBMAN-SACKS DISEASE _____ and _______ valvulitis occuring in _____
Mitral & Tricuspid SLE
26
LIEBMAN-SACKS DISEASE Morphology Lesions are (small or large?) (1-4mm) Lesions are (Sterile or non-sterile?) and (Granular or Agranular?)
Small Sterile Granular
27
LIEBMAN-SACKS DISEASE Morphology Lesions are Located in _____ surface of _______ Lesions Consist of ______ material that contains ________ bodies
under AV valves eosinophilic; haematoxylin
28
LIEBMAN-SACKS DISEASE Morphology Intense ______ with _________ Vegetations rarely ______ but often become ______
valvulitis; fibrinoid necrosis embolises; fibrosed
29
Differentiate between Rheumatic fever, NBTE, LSE, and infective endocarditis In terms of lesions
Small, warty Firm, Friable Small, warty Friable Medium sized (small) Flat, verrucous Irregular Large Bulky Irregular
30
Differentiate between Rheumatic fever, NBTE, LSE, and infective endocarditis In terms of sterility
Sterile Sterile Sterile Non-Sterile
31
Differentiate between Rheumatic fever, NBTE, LSE, and infective endocarditis In terms of embolization
Embolization is uncommon Embolization is uncommon Embolization is uncommon Embolization is common
32
Differentiate between Rheumatic fever, NBTE, LSE, and infective endocarditis In terms of conditions where it is found
In rheumatic heart disease In Cas (M3-AML, pancreatic CA, DVT, TS In SLE In IE
33
Differentiate between Rheumatic fever, NBTE, LSE, and infective endocarditis In terms of location
Along lines of closure Along lines of closure Both surfaces of cusp but more of the under surafce…less commonly mural endocardium Vegetations on the valve cusps.Less often on mural endocardium
34
_______ is the most common overall cause of infectious endocarditis
Streptococcus viridans
35
_______ is the most common cause of infectious endocarditis in IV drug users
Staphylococcus aureus
36
Staphylococcus aureus most commonly infects ______ valve
Tricuspid
37
Staphylococcus epidermidis is associated with endocarditis of _________ Streptococcus bovis is associated with endocarditis in patients with underlying ___________
prosthetic valves. colorectal carcinoma.
38
_________ organisms are associated with endocarditis with negative blood cultures.
HACEK
39
HACEK organisms (______,_______,______,______,______)
Haemophilus, Actinobacillus, Cardiobacterium, Eikenella, Kingella

House AMP (66 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions