Aetiology Pathogenesis Flashcards
Aetiology
This refers to the ______
•It is broadly classified into _______ or ______
cause of a disease
inherited or acquired
Majority of diseases have complex aetiology
T/F
T
Acquired causes of diseases can be classified into:
• _____
•_______
•________
•________
physical
Dietary
Chemical
microbiologic agents
Pathophysiology refers to the ________ associated with or resulting from disease or injury and the scientific study of such
changes.
functional changes
Pathophysiology provides the link between _______ and _____
basic sciences and its application to clinical practice
Pathophysiology looks at diseases as manifestation of ______
disordered function
Pathophysiology explains the basis for symptoms and signs
T/F
T
Difference between Pathophysiology and pathology
pathology studies the structural,
biochemical and functional changes in
cells, tissue and organs in disease states,
PP does all with the exclusion of
structural changes
Pathogenesis is defined as the _____ that underlie disease from _________ to ______
against them, resulting in manifestation of the disease
mechanisms
the effect of the aetiological agents to the reactions of the body
Disease manifestation
From sub clinical (_______) to _______ stage to _______
Latent incubation
Clinical
Recovery or complications
When there is encroachment on normal biological processes, the earliest manifestations are most
often ______(____) which may be nonspecific
E.g. ______ in gastric cancer,
•Identifiable aberrations( ______ ) in the patient (_____)
subjective(symptoms)
dyspepsia
objective
signs
A Lesion refers to demonstrable _____ change produced in the course of a disease which may be ______ or ______
structural
macroscopic or microscopic
Diseases
Dynamic or static?
Diseases are dynamic, not static
Most causes of diseases are (acquired or inherited?) from the _____
Acquired
environment
H.pylori
is a _____ shaped, microaerophilic, gram
_______ bacterium.
• Transmitted via _____ and _____ route
spiral; negative
oral-oral and faeco-oral route