Inheritance - mutations Flashcards
what is a change to the base?
a mutation
when do mutations happen?
all the time
why can the shape of the protein not change sometimes when a single base has changed?
different base triplets can encode for the same amino acids in. mutations has had no affect on the shape or function
most mutations have __ _____ on the function of the protein
no effect
what can happen if a triplet base changes and it changes the shape of the protein?
it now has a different function. for example the active site of an enzyme may change so it can no longer attach to the substrate
what can happen if a mutation changes the shape of a structural protein?
it can lose its strength such as collagen
chromosomes also contain __-______ parts of DNA
non-coding.
these regions switch genes on and off (tell genes when to produce proteins)
what can mutations in non-coding regions affect?
how genes are switched on or off.a gene may be turned on when it should be turned off. in this case, the cell would produce a protein that is not meant to have at that time. can have a very significant effect on a cell eg uncontrolled mitosis leading to cancer