Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

DIT > immunology > Flashcards

immunology Flashcards

1
Q

molecules expressed on antigen presenting dendritic cells

A

MHC 1 and II
B7
CD40

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

EM of a dendritic cell with Langerhans cell histiocytosis

A

Birbeck granule (tennis racket cells)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

surface markers on B cells

A

CD19, 20, 21
CD 40
CDB7
IgM, IgD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What initiates V(D)J recombination

A

RAG-1 or RAG-2 that recognize recombination signal sequences (RSS)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what viral vaccines may be dangerous to egg allergy

A

influenze and yellow fever

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

precursor of 6-mercaptopurine

A

azathioprine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Ab that binds to CD3 on t cells

A

muromonab

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Ab that binds IL-2 receptor on activated T cells

A

daclizumab

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

inhibits inosine monophophate (IMP) dehydrogenase

A

mycophenolate mofetil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

inhibits calcineurin resulting in the loss of IL-2 and blocks T cell differentiation and activation

A

cyclosporine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

binds FK-binding protein (FKBP) leading to loss of IL-2 production

A

tacrolimus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

binds FKBP12 leading to inhibiton of mTOR and T cell proliferation

A

sirolimus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

used for lupus nephritis

A

azathioprine

mycophenolate and cyclosporine off label

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

metabolized by xanthine oxidase, therefore allopurinol increases the toxicity

A

azathioprine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

X-linked immunodeficiencies

A 
WACH
wiskott-aldrich
Bruton Agammaglobulinemia
\+/- chronic granulomatous disease
\+/- hyper IgM syndrome
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

wiskott-aldrich syndrome

A 
WAITER
Wiskott
aldrich
immunodeficiency
thrombocytopenia and purpura
eczema
recurrent pyogenic infections
increased IgA, decreased IgM
17
Q

chronic granulomatous disease cause and susceptible organisms

A

no NADPH oxidase
catalase + organisms:
S. aureus, E. coli, Aspargillus, Klebsiella, Candida

18
Q

young pt with tetany from hypocalcemia, and candidiasis resulting from immunosuppression

A

thymic aplasia-> T cell deficiency

19
Q

eczema, recurrent cold abscesses, high serum IgE

A

hyperimmunoglobulin E (Job disease)

20
Q

large lysosomal vesicles in phagocytes

A 
Chediak-Higashi 
defective LYST (lysosomal transport) gene

DIT (28 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions