IBS

Question 1

epidemiology?

Answer 1

• occurs in 20% of population
• younger adults
• F>M

Question 2

symptoms?

Answer 2

• abdo pain/discomfort
  
  • relieved by opening bowels or
  • associated w a change in bowel habit

+ 2 of:

• abnormal stool passage
• bloating
• PR mucus
• worse symptoms after eating

Question 3

diagnosis?

Answer 3

exclude other pathology

• Normal FBC, ESR & CRP blood tests
• Faecal calprotectin negative
• Negative coeliac disease serology
• Cancer is not suspected or excluded if suspected

Question 4

Mx?

Answer 4

1. loperamide for diarrhoea, linaclotide for constipation, buscopan for cramps
2. tricyclic antidepressants
3. SSRI

+ general healthy diet and exercise advice