Dysphagia & Achalasia Flashcards
what is dysphagia?
difficulty swallowing
DDx?
just some…
- pharyngitis
- pharyngeal pouch
- oesophageal candidiasis
- Diffuse oesophageal spasm
- GORD
- hiatus hernia
- stroke
what may be in the history of diffuse oesophageal spasm?
- dyspahgia intermittent and non-progressive
- chest pain indistinguishable from cardiac chest pain, relieved by nitroglycerin & assoc w meals
what may be in the history of oesophageal candidiasis?
- may be history of corticosteroid, abx, inhaler use or immunocompromised
- creamy white / yellow plaques seen in oropharynx or hypopharynx
cause if dysphagia for BOTH solids and liquids at start: yes and no
yes–> motility disorder
no–> solids>liquids: stricture
cause if difficulty making swallowing movements?
bulbar palsy
cause if constant and worsening?
malignant stricture
cause if odynophagia?
cancer, ulcer or spasm
pathophysiology of achalasia?
- degeneration of myenteric plexus
- loss of oesophageal peristalsis and failure of LOS to relax in response to swallowing
- = food stagnates in lower part of oesophagus & regurgitates
aetiology of achalasia?
- idiopathic - commonest
- oesophageal cancer
presentation of achalasia?
- intermittent dysphagia (both solids and liquids)
- regurgitation
- retrosternal chest pain
Ix for achalasia?
- endoscopy (exclude malignancy)
- barium swallow
- oesophageal manometry
what is manometry?
investigation to measure function of LOS
outline what may be seen in barium swallow and manometry in achalasia
- barium swallow
- dilated oesophagus w tapered beak-like narrowing
- manometry
- incomplete relaxation of LOS + aperistalsis + higher pressure at GOJ
Mx of achalasia?
if symptomatic…
- medical: nitrate / CCB
- botulinum toxin
- surgical: endoscopic dilatation (POEM) / Heller’s myotomy