Cholangiocarcinoma Flashcards

1
Q

what is it?

A

malignancy of biliary tree - intra or extra hepatic

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2
Q

aetiology?

A

associated with PSC and hence IBD

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3
Q

epidemiology?

A
  • 20% of overall liver cancers
  • tends to present in over 50 y/o
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4
Q

symptoms?

A
  • of painless obstructive jaundice
  • dull abdo pain
  • wt loss
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5
Q

signs?

A
  • abdo mass
  • hepatomegaly
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6
Q

tumour marker?

A

CA19-9

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7
Q

Ix?

A
  • Liver USS
  • CT/MRI to stage
  • ERCP to take biopsies / brushings
  • tumour marker
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8
Q

Mx?

A
  • early disease - potentially cured w surgical resection
  • advanced disease- symptom control w ERCP to place stent

resistant to chemo/radiotherapy

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9
Q

prognosis?

A

v poor unless diagnosed early

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