Gastric cancer Flashcards

1
Q

histological type?

A

adenocarcinoma

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2
Q

aetiology?

A
  • Previous H.Pylori infection
  • smoking
  • certain foods
  • FH
  • Previous gastric resection
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3
Q

Epidemiology?

A
  • 2nd commonest cancer of alimentary tract
  • most common in 50-70
  • M>F
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4
Q

Symptoms?

A
  • wt loss
  • abdo pain
  • dysphagia (if tumour proximal/ in GOJ)
  • dyspepsia
  • early satiety
  • N&V
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5
Q

Signs?

A
  • epigastric mass

If mets:

  • hepatomegaly or palpable virchows node
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6
Q

Ix?

A
  • endoscopy w biopsy
  • CT chest /abdo to stage
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7
Q

Spread?

A
  • Direct- spread to surrounding structures
  • Lymphatic- spread to regional lymph nodes
  • Blood spread- Liver
  • Transcoelomic spread- spread within peritoneal cavity
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8
Q

mX?

A

Surgical and chemo

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9
Q

complications?

A
  • bleeding
  • obstruction
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10
Q

what is a complication post gastrectomy?

A

“dumping syndrome”

when stomach empties its contents into duodenum faster than normal, also known as rapid gastric emptying. People experience symptoms like nausea and abdominal cramping

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11
Q

prognosis?

A

v poor –> 5 year survival less than 20%

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