How DNA forms Chromosomes and other important information Flashcards

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1
Q

purines

A

double rings such as Adenine Guanine

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2
Q

Pyrimidine

A

single ring thymine cytosine

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3
Q

what is a Glycosyl

A

A glycosidic bond exists in the DNA molecule between sugar and nitrogen base.

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4
Q

Chromatin consists of approximately ___ protein and ___ DNA

A

60% and 40%

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5
Q

a chromosome is a long strand of ____ and ______ made of _______ nucleotides

A

DNA and Protein and 300 million

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6
Q

how are chromosomes organized

what is a nucleosome

how is the DNA double helix strand strongly attracted to the histones

what do series of nucleosomes do

and what happens after

A

so the DNA is coiled to fit inside nucleus and every 200 nucleotides the DNA double strand is coiled around a central histone ( 8 histones together) and is held by another histone (Hi)

nucleosomes are complex of histones coiled by DNA

it has a negative charge and therefore meaning histones have positive charges

series of nucleosomes coil into chromatin fibres

chromatin fibres fold and supercoil

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7
Q

humans contain how many of what chromosomes

A

46 ( 44 somatic, 2 are sex chromosomes)

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8
Q

how many genes exist within the human genome

A

42 000 and 95+ is noncoding

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9
Q

what are VNTR’s (variable number tandem repeats) and where can they be located

and what are they also known as

A

VNTR’s are sequences of base pairs that repeat, the length varies as does their position within the genome

you can find them in noncoding regions

also known as microsatelites

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10
Q

what are introns and exons

A

introns are sequences of DNA removed from the mRNA transcript
and do not code for a protein

exons are genes which do encode the amino acid sequence for protein production

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11
Q

what is a telomere

A

long sequences of repetitive noncoding DNA are found at the ends of chromosomes, called telomeres, to serve and protect DNA from losing nucleotides during replication

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12
Q

what is the monomer of DNA

A

Nucleotide

but can also be polymers when joined together

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13
Q

why is DNA called deoxyribonucleic acid instead of ribonucleic acid

A

because there is no oxygen at the second carbon of deoxyribose sugar

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14
Q

what is the bond name that attaches the rungs of the ladder to the sides of the ladder

A

glycosyl bonds as it is between deoxyribose sugar and nitrogenous base

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