HOOFDSTUK 28 + 29 Flashcards

DIURETICA

1
Q

proximaal werkende diuretica

A

acetazolamide
= waterreabsorptie blokkeren

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2
Q

loepdiuretica

A

= furosemide
= bumetanide
= torsemide
= ethacrinezuur

  • lisdiuretica
  • blokkeren Na-Cl-K-cotransport
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3
Q

distaal werkende diuretica

A

= thiazide diuretica
= hydrochlorothiazide
= chlorothiazide
= chlorthalidone, metolazone

blokkeren Na-Cl-cotransporter

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4
Q

2e deel van distaal werkende diuretica

A

= kaliumsparende diuretica
= sprionolactone
= eplerenone
= triamterene
= amiloride

bokkers van aldosteron
K-opstapeling ! K-arm dieet

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5
Q

verzamelbuis = ADH antagonisten

A

= demeclocycline
= tolvaptan
= conlvaptan
- aquaretica
- zuivere waterreabsorptie blokkeren

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6
Q

acidose
alkalose

A

acidose = onder 7,38
alkalose = boven 7,42

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7
Q

toename
afname
van CO2

A

toename CO2 = acidose
afname CO2 = alkalose

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8
Q

bescherming tegen zuur-base?

A
  • bufers
  • ventilatie
  • nier
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9
Q

buffer?
- binding?

A

hemoglobine bindt op proton
Eigenschappen van Hb veranderen bij binding
Henderson-hasselbach vgl

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10
Q

Henderson-Hasselbach vgl?

A

pH = pKa + log (HCO3)/cte*pCO2

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11
Q

hoe beschermt de nier ons?

A

HCO3 bijmaken
CO2 daalt
HCO3 gaat verloren want het verlaat het lichaam als CO2 thv de long

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12
Q

hoe beschermt de long ons?

A
  • houdt CO2 constant
  • CO2 reguleren
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13
Q

als HCO3 daalt …

A

pH daalt

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14
Q

als BD stijgt

A

K daalt
= meer buffer in bloed

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15
Q

lage BD

A

= weefselhypoxie
= acidose

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16
Q

aldosteron

A

= oplossen van hyperkaliëmie

17
Q

angiotensine

A

= meer buffer

18
Q

combinatie aldosteron en angiotensine

A

= bloeddruk stijgt