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Maternal Child And Health Nursing > HODGKIN DISEASE > Flashcards

HODGKIN DISEASE Flashcards

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1
Q

large, multinucleated cells that are probably nonfunctioning monocyte-macrophage cells

A

Reed-Sternberg Cells

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2
Q

Why are Reed-Sternberg Cells abnormal?

A

*because they lack both B- ang T-lymphocyte surface markers
*cannot produce immunoglobulins

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3
Q

It is rarely seen in children younger than

A

younger than 7 years

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4
Q

Metastasis is through

A

lymphatic channels

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5
Q

If Hodgkin Disease is left untreated what will happen?

A

it will spread to lungs, liver, and bone marrow

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6
Q

Symptoms of Hodgkin Disease usually begin with

A

enlargement of only one painless, enlarged, rubbery lymph node.

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7
Q

In Hodgkin Disease, the child may report accompanying symptoms of

A

*anorexia
*malaise
*night sweats
*unintentional loss of weight

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8
Q

Hodgkin Disease is confirmed by

A

biopsy of the lymph nodes

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9
Q

The ________ may reveal enlarged mediastinal nodes

A

chest CT scan

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10
Q

_________ may reveal enlarged lymph nodes of the abdomen

A

abdominal CT scan

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11
Q

are typically used to stage and monitor response to Hodgkin disease treatment

A

PET scans

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12
Q

is a nuclear medicine imaging modality that utilizes injected radiolabeled molecules

A

PET scan

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13
Q

PET scan

A

Positron Emission Tomography (PET)

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14
Q

Preparation for the scan will include a

A

period of fasting followed by radionuclide injection, a dwell period, and then the scan

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15
Q

Hours of fasting for the PET scan

A

usually 6 to 8 hours

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16
Q

Today’s standard of treatment for Hodgkin Disease

A

Combination therapy: using a combination of chemotherapy agents, with radiation reserved for those who have a limited response to chemotherapy

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17
Q

children diagnosed with Hodgkin Disease will have __________ to gauge the response to treatment and determine the amount of therapy needed.

A

Intermittent PET/CT scans

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18
Q

Current therapy for Hodgkin Disease results in what survival rate for children

A

98% 5-year survival rate for children; and up to 50% with relapsed or refractory disease

19
Q

If relapse occurs, what will be needed for Hodgkin Disease?

A

additional chemotherapy, immunotherapy, radiation, or bone marrow transplantation will be utilized.

20
Q

ESR

A

erythrocyte sedimentation rate (ESR)

21
Q

with Hodgkin Disease, lymphocytes proliferate

A

in the lymph glands

22
Q

what is the typical utilized injected radiolabeled molecule

A

glucose

23
Q

Hodgkin disease is now referred to as

A

Hodgkin Lymphoma

24
Q

The disease manifests in two primary subtypes:

A

*Classical Hodgkin Lymphoma
*less frequent nodular lymphocyte-predominant Hodgkin Lymphoma

25
Q

common areas of manifestation of the lymph nodes of the disease

A

*neck
*armpit
*groin

26
Q

Hodgkin disease is most commonly diagnosed in what age

A

early adulthood (between ages 15 and 40) and late adulthood (after age 55)

27
Q

Hodgkin disease occurs slightly more frequently in what gender

A

Males

28
Q

EBV infection

A

Epstein-Barr Virus infection

29
Q

causes infectious
mononucleosis (mono)

A

Epstein-Barr Virus (EBV) Infection

30
Q

Epstein-Barr Virus (EBV) Infection

A

causes infectious
mononucleosis (mono)

31
Q

Some autoimmune diseases, such as __________ have been associated with a higher risk of Hodgkin’s disease.

A

*rheumatoid arthritis
*systemic lupus erythematosus (SLE)
*celiac disease

32
Q

unintentional weight loss of body weight over a period of six months or less can occur in individuals with Hodgkin’s disease.

A

weight loss of 10% or more

33
Q

The abnormal lymphocytes in Hodgkin’s disease release inflammatory
substances called

A

cytokines

34
Q

can make you feel tired and unwell,
leading to decreased desire to eat.

A

Cytokines

35
Q

is a rare condition fever reported in patients with Hodgkin’s lymphoma

A

Pel-Ebstein fever or Pelle Epstein Fever

36
Q

Treatment for Hodgkin Disease

A

A - Adriamycin
B - Bleomycin
V - Vinblastine
D - Dacarbazine

37
Q

Treatment for stage I and II

A

2-4 cycles of ABVD + Radiotherapy

38
Q

Treatment for Stage III and IV

A

6-8 cycles + Radiation

39
Q

By Ann-Arbor classification, Stage I is

A

Single Site: one lymph node or one extralymphatic site

40
Q

By Ann-Arbor classification, Stage II is

A

≥ 2 L.Ns on same side of diaphragm

41
Q

By Ann-Arbor classification, Stage III is

A

L.Ns on both sides

42
Q

By Ann-Arbor classification, Stage IV is

A

Diffuse, one or more extralymphatic tissue

43
Q

How to diagnose Hodgkin Lymphoma

A

*Complete Blood Count Test
*Physical Examination
*Imaging test (X-ray or PET/CT scan)
*Biopsy

43
Q

Lymph nodes of the Hodgkin Disease usually starts at what area?

A

cervical lymph nodes

Maternal Child And Health Nursing (46 decks)

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