Herbs and the GI Flashcards
Tones or benefits the function of the stomach; increases appetite:
Stomachic
Tastes bitter; stimulates digestion:
Bitters
Prevents formation of/relieves gas:
Carminative
Facilitates bowel movement:
Laxative
Evacuates the colon:
Purgative
Cathartic
Causes vomiting:
Emetic
Relieves nausea; stops vomiting:
Antiemetic
Kills parasitic worms in the GI tract:
Antihelminthic
Digestive processes in the mouth:
- Mastication
- Saliva - amylase
- Taste - stimulates brain reflex to trigger digestion
Digestive processes in the stomach:
- Protein digestion - HCl & pepsin
- Gastrin - stimulates HCl prodxn
- Gustducin - transduces bitter/sweet/umami
- Ghrelin - inc hunger/motility/mucosal cell proliferation; mucosal AI
- Churns food
Digestive processes in the duodenum:
- CCK - prodxn/release of pancreatic enzymes/bile d/t fat & amino acids
- Secretin - dec. gastric emptying; stim pancreatic juices
- GIP - dec. gastric emptying
Digestive processes of the liver:
Gall bladder:
Liver - produces bile -> emulsifies fat
Gall bladder - stores & excretes bile
Digestive processes of the pancreas:
- H2CO3 - Neutralizes acids
* Enzymes - lipase, nuclease, phospholipase, trypsinogen, chymotrypsinogen, elastase, amylase, sterol esterase.
Digestive processes of the intestines:
- Assimilation (absorption?)
* Elimination
Where do bitters work? How?
In the mouth; Receptors on the tongue / oral mucosa stimulate the production of saliva, transmit signals to the brain -> stimulates digestive processes through vagal efferents
Bitters stimulate what processes?
- Inc ghrelin (inc hunger, satiety cycle)
- Inc CCK (bile secretion, pancreatic enzymes)
- Stimulates motility
- Anti-inflammatory to GI mucosa
- Stimulates proliferation of mucosal cells
What is the “quintessential” digestive bitter:
Gentiana lutea (gentian)
Name some alterative bitters:
- Taraxacum officinale (dandelion)
- Cynara scolymus (artichoke)
- Rumex crispus (yellow dock)
- Mahonia sp (Oregon grape)
Name some bitter carminatives:
- Matricaria recutita (chamomile)
* Angelica archangelica (angelica)
Gentian - actions:
- Bitter (stim digestion)
- Analgesic
- Anti-inflammatory
- Cholagogue
Gentian constituents:
- Secoiridoid glycosides (amarogentin, gentiopicrin, gentiopicroside, swertiamarin)
Citrus peel constituents:
- Flavonoid glycosides (neohesperidin, naringin)
- Non-bitter flavonoids (hesperidin, rutoside, sinensetin, nobiletin, tangeritin)
- Essential oil (limonene)
- Pectins
- Furanocoumarins
- Phenols (polymethoxylated flavones, hydroxycinnamates)
Citrus peel is classically used as a bitter tonic for:
dyspepsia
loss of appetite
Name some aromatic bitters:
- Zingiber officinale (ginger)
- Citrus sinensis (sweet orange)
- Citrus aurantium (bitter orange)
- Elettaria cardamomum (cardamom)
Bitter orange contains ____________ (mainly bergapten) that are ______________ in fair-skinned people.
furanocoumarins
photosensitizing
not found in sweet orange
D-limonene is used in the tx of ____________ because it is a solvent of _____________.
It is also used to treat ________ because it promotes __________.
gallstones
cholesterol
GERD
peristalsis
Citrus peel - energetics:
sour
bitter
dry
cool or warm (depends on individual)
Bitters - indications:
- dyspepsia
- intestinal atony
- hypochlorhydria
- malabsorption
Bitters - contraindications:
- hyperchlorhydria
- acute gastritis
- acute diarrhea
- acute IBD flare
- acute peptic ulcer
- Zollinger-Ellison syndrome
- concomitant acid blocker drug therapy
Carminative herbs have mild _____________ effects, largely due to the ______________ they contain.
antispasmodic
volatile oils
Carminative herbs:
- Foeniculum vulgare (fennel)
- Pimpinella anisum (anise)
- Mentha piperita (peppermint)
- Mentha spicata (spearmint)
- Zingiber officinale (ginger)
- Matricaria recutita (chamomile)
- Angelica archangelica (angelica)
- Elettaria cardamomum (cardamom)
Fennel - actions:
- antispasmodic
- anti-inflammatory
- carminative
- galactogogue
- bitter
Fennel - energetics:
warming
aromatic
bitter
sweet
Fennel - constituents:
- 50-70% trans-anethole (sweet)
*
Chamomile - actions:
- Carminative
- stomachic
- antiemetic
- antispasmodic
- anti-inflammatory
- sedative
- nervine
- anti-ulcerogenic
- bitter
Chamomile - constituents:
sesquiterpenes (alpha-bisabolol & chamazulene, matricin, apigenin)
Chamomile - indications:
- nervous manifestations of dentition
- otitis media
- rheumatic / neuralgic pain
- abdominal neuroses
- hysteria
- infantile convulsion
Ginger - actions:
- ANTIEMETIC
- carminative
- stomachic
- anti-inflammatory
- analgesic
- diaphoretic
- diuretic
- antimicrobial
- expectorant
- antitussive
- decreases platelet aggregation
- increases digestive enzyme activity
Ginger - constituents:
- monocyclic sesquiterpenes (zingiberene, zingiberole, gingerol, shogoal, phellandrene, borneol, cineole, citral)
- resins
- mucilage