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Fundamentals 1 > Gut Histology > Flashcards

Gut Histology Flashcards

1
Q

What does most epithelial tissue line?

A

cavitities and surfaces

apical side touches the lumen

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2
Q

Basement membrane

A

normally separates epithelial tissue from connective tissue lamina propria

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3
Q

Is basement membrane an actual membrane?

A

no

it is made of extracellular material

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4
Q

What does basement membrane bind to?

A

hemidesosomes

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5
Q

What is main collagen type of connective tissue?

A

type I collagen

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6
Q

Do epithelial cells contain an abundance of collagen?

A

no

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7
Q

Does epithelial tissue secrete components of basal lamina?

A

yes

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8
Q

What are microvilli made of?

A

actin filaments

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9
Q

What type of cells have microvilli?

A

intestine

can form a “brush border”

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10
Q

What type of cells have cilia?

A

respiratory tract cells

important for mucus movement

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11
Q

What is true in general of cilia?

A

they help with movement

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12
Q

Simple epithelia

A

single layer of cells, all of which rest on basement membrane

can have different shapes

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13
Q

Where is simple epithelia normally found?

A

where exchanges occur

such as blood capillaries and air spaces of lungs

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14
Q

Simple squamous epithelial cells

A

mesothelium and endothelium

blood cavities

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15
Q

Simple squamous cell shape

A

wider than they are tall

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16
Q

Simple cuboidal epithelial cells

A

found in many of the ducts

ex: parotid gland

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17
Q

Simple columnar cells

A

normally found in the digestive tract

18
Q

Where is the brush border found?

A

normally in the gut

19
Q

What is brush border made of?

A

actin

20
Q

Pseudostratified epithelium

A

NOT stratified

all cells do touch the basement membrane

the nuclei are just at different heights

21
Q

Connective vs. epithelial tissue

A

connective tissue is much less dense than epithelial

22
Q

Stratified epithelia

A

multiple layers of epithelial cells but only the basal layer of cells rests on basement membrane

23
Q

Stratified squamous

A

top layer consists of flattened cells

24
Q

two types of stratified squamous

A

1) Keratinized
2) Non-keratinized

25
Q

where are non-keratinized stratified squamous cells found?

A

moist surfaces that are still exposed to elements

like the mouth

26
Q

transitional epithelial cells are found?

A

urinary tract / bladder

27
Q

How can you identify transitional epithelial cells?

A

there are no neat rows to the layers

however, there are still multiple layers

28
Q

What can transitional epithelial cells often be confused with?

A

stratified cubodial

however, this doesn’t have neat rows

29
Q

Mucosae

A

generally moist regions that are coated with mucus

30
Q

layers of GI tube from inner to outer

A

mucosa (includes epithelial)

submucosa

muscularis externa / propria

adventitia OR serosa

31
Q

What are the 3 layers of the mucosa (innermost layer)?

A

epithelium

lamina propria

muscularis mucosae

32
Q

Where is connective tissue?

A

in the lamina propria

in the submucosa (primarily)

33
Q

Esophageous epithelial cells

A

stratified squamous

allows us to transport food

34
Q

How do you stain connective tissue?

A

you actually stain extracellular products not the tissues themselves

35
Q

What does muscularis mucosae stain?

A

pink / red

36
Q

Serosa vs. adventitia location

A

adventitia is outermost layer of esophagus

serosa is outermost layer of most of the digestive tract (visceral peritoneum)

37
Q

Adventitia appearance

A

blends into the surrounding tissue

no defined borders

38
Q

Epithelium of the colon

A

Simple column cells

specialize in water absorption

have crypts

39
Q

Crypts

A

straight tubular elements in the epithelial layer of colon tissue

40
Q

Submucosa of the colon

A

expansive

contains many large blood vessels to transport water out of GI

41
Q

Serosa of colon

A

simple squamous epithelial covering

often CANNOT see on slides

42
Q

Pseudomembranes

A

composed of inflammatory cells and debris in locations where the mucosa has been injured and denuded

Fundamentals 1 (29 decks)

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