Gut Histology Flashcards

1
Q

What does most epithelial tissue line?

A

cavitities and surfaces

apical side touches the lumen

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2
Q

Basement membrane

A

normally separates epithelial tissue from connective tissue lamina propria

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3
Q

Is basement membrane an actual membrane?

A

no

it is made of extracellular material

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4
Q

What does basement membrane bind to?

A

hemidesosomes

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5
Q

What is main collagen type of connective tissue?

A

type I collagen

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6
Q

Do epithelial cells contain an abundance of collagen?

A

no

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7
Q

Does epithelial tissue secrete components of basal lamina?

A

yes

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8
Q

What are microvilli made of?

A

actin filaments

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9
Q

What type of cells have microvilli?

A

intestine

can form a “brush border”

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10
Q

What type of cells have cilia?

A

respiratory tract cells

important for mucus movement

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11
Q

What is true in general of cilia?

A

they help with movement

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12
Q

Simple epithelia

A

single layer of cells, all of which rest on basement membrane

can have different shapes

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13
Q

Where is simple epithelia normally found?

A

where exchanges occur

such as blood capillaries and air spaces of lungs

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14
Q

Simple squamous epithelial cells

A

mesothelium and endothelium

blood cavities

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15
Q

Simple squamous cell shape

A

wider than they are tall

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16
Q

Simple cuboidal epithelial cells

A

found in many of the ducts

ex: parotid gland

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17
Q

Simple columnar cells

A

normally found in the digestive tract

18
Q

Where is the brush border found?

A

normally in the gut

19
Q

What is brush border made of?

20
Q

Pseudostratified epithelium

A

NOT stratified

all cells do touch the basement membrane

the nuclei are just at different heights

21
Q

Connective vs. epithelial tissue

A

connective tissue is much less dense than epithelial

22
Q

Stratified epithelia

A

multiple layers of epithelial cells but only the basal layer of cells rests on basement membrane

23
Q

Stratified squamous

A

top layer consists of flattened cells

24
Q

two types of stratified squamous

A

1) Keratinized
2) Non-keratinized

25
where are non-keratinized stratified squamous cells found?
moist surfaces that are still exposed to elements like the mouth
26
transitional epithelial cells are found?
urinary tract / bladder
27
How can you identify transitional epithelial cells?
there are no neat rows to the layers however, there are still multiple layers
28
What can transitional epithelial cells often be confused with?
stratified cubodial however, this doesn't have neat rows
29
Mucosae
generally moist regions that are coated with mucus
30
layers of GI tube from inner to outer
mucosa (includes epithelial) submucosa muscularis externa / propria adventitia OR serosa
31
What are the 3 layers of the mucosa (innermost layer)?
epithelium lamina propria muscularis mucosae
32
Where is connective tissue?
in the lamina propria in the submucosa (primarily)
33
Esophageous epithelial cells
stratified squamous allows us to transport food
34
How do you stain connective tissue?
you actually stain extracellular products not the tissues themselves
35
What does muscularis mucosae stain?
pink / red
36
Serosa vs. adventitia location
adventitia is outermost layer of esophagus serosa is outermost layer of most of the digestive tract (visceral peritoneum)
37
Adventitia appearance
blends into the surrounding tissue no defined borders
38
Epithelium of the colon
Simple column cells specialize in water absorption have crypts
39
Crypts
straight tubular elements in the epithelial layer of colon tissue
40
Submucosa of the colon
expansive contains many large blood vessels to transport water out of GI
41
Serosa of colon
simple squamous epithelial covering often CANNOT see on slides
42
Pseudomembranes
composed of inflammatory cells and debris in locations where the mucosa has been injured and denuded