GI 8: Hepatic, Pancreatic and Intestinal Secretions Flashcards

1
Q

small intestine secretions come from the ___

A

crypt of Lieberkuhn

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2
Q

goblet cells secrete ___

A

mucous

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3
Q

paneth cells secrete ___ and are capable of ___

A

lysozymes; phagocytosis

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4
Q

enteroendocrine cells secrete the hormones __, ___ or ___

A

secretin; cholecystokinin ; GIP

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5
Q

secreti is secreted by )__ cells

A

s

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6
Q

CCK is secreted by ___ cells

A

I

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7
Q

GIP is secreted by ___ cells

A

K

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8
Q

the pH of secretions of the small intestine is slightly ___

A

alkaline

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9
Q

secretions of the small intestine are mostly regulated by local reflexes w/I the ENS initiated by __ or ___ stimuli

A

irritative or tactile

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10
Q

bile is a substance produced by the __, stored in the __ and secreted in the ___

A

liver; gallbladder; small intestine

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11
Q

bile contains what 6 components?

A
  1. bile salts
  2. lecithin
  3. HCO3
  4. cholesterol
  5. bilirubin
    trace metals
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12
Q

what is the function of bile salts and lecithin?

A

solublize and emulsify fat

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13
Q

what s the function of bicarbonate?

A

neutralize stomach acid

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14
Q

what is the function of cholesterol, bilirubin, trace metals?

A

excreted as waste in faces

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15
Q

what are the 3 main bile functions?

A
  1. lipid emulsion
  2. pH
  3. waste excretion
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16
Q

jaundice is caused by an excess of __

A

bilirubin

17
Q

parasympathetic vagus nerve and ENS stimulation induces ____ by the liver and release of bile from the ___

A

production; gallbladder

18
Q

secretin, produced by the ____, triggers the bile ___ in the liver

A

duodenum; synthesis

19
Q

CCK produced by the ___ triggers the contraction of the ___ and the relaxation of the ___, resulting in the release of bile

A

duodenum; gallbladder; sphincter of oddi

20
Q

95% of bile salts are reabsorbed in the ___ and are returned to the liver, where they will trigger___

A

ileum; more secretion of bile

21
Q

t/f both the gallbladder and pancreas use the sphincter of oddi

A

true

22
Q

pancreatic secretions have what 2 components?

A

aqueous and enzyme rich

23
Q

the aqueous component of pacreatic secretions is produced by the ___ cells and contains HCO3- that neutralize acidic chymeand pepsin while activating pancreatic enzyme

A

duct

24
Q

___ cells produce the enzyme rich components of pancreatic secretions

A

acinar

25
Q

HCO3 crosses the apical memnbrane by the ___ transporter

A

Na/HCO3

26
Q

trypsin and chymotrypsin break down ___

A

proteins

27
Q

pancreatic amylase breaks down the ___

A

carbs

28
Q

procolipase most be activated by_____ to ____ to help break down lipids

A

trypsin; colipse

29
Q

trypsinogen is activate by ____ and it becomes activate d in ______

A

enteropeptidases; duodenum

30
Q

____ enzyme can further catalyses the reactions: trypsinogen to trypsosin, procarbboxypeptidases to phospholipase and phospholipase to phospholipase

A

trypisin

31
Q

acidic chyme stimulates the release of ___

A

HCO3-

32
Q

peptides in the duodenum stimulate the release of ___

A

enzymes

33
Q

lipids (soap) in the duodenum stimulates the release of ___

A

HCO3

34
Q

both secretin and CCK ____ (decrease/increas) gastric sole

A

decrees

35
Q

SECRETIN STIMULATES THE ____ OF THE BILE AND THE CCK STIMULATES THE ___ FROM THE VISUAL FELLING

A

release