Genitourinary #1 Flashcards
Urge incontinence is due to _____ and is MC in ______
Detrusor muscle overactivity and is most common in older women
Management of urge incontinence
- Bladder training
- Diet (avoid spicy foods, chocolate, alcohol, and caffeine)
- Antimuscarinics: Tolterodine, Oxybutynin
- Mirabegron
- TCA
- Surgical: injection of Botox, bladder augmentation
Overflow incontinence is due to _____ and some common etiologies include…
Bladder detrusor muscle under activity
-Neurological disorders, autonomic dysfunction, BPH, prior pelvic floor surgery
How does overflow incontinence differ from the other types of incontinence?
-Loss of urine with no warning (as in urge) or triggers (as in stress)
What is the gold standard to diagnose a patient with overflow incontinence?
Post void residual > 200 mL
Treatment for overflow incontinence
- Intermittent or indwelling catheter first-line
- Cholinergics: Bethanechol (increases detrusor muscle activity)
What is the pathophysiology of stress incontinence?
-Leakage of urine that occurs once increased abdominal pressure > urethtral pressure
When does stress incontinence occur usually?
-Exertion, coughing, sneezing, laughing
Common etiologies of stress incontinence include
- Laxity of pelvic floor muscles (childbirth, surgery)
- Urethral hyper mobility
Treatment for stress incontinence
- Pelvic floor (Kegel) exercises
- Lifestyle modifications: weight loss, smoking cessation, drink small amounts of water throughout the day
- Pessaries
- Surgery: Midurethral sling (definitive)
Uterine Prolapse is when the uterus herniates into the vagina. Risk factors include weakness of pelvic support structures such as after childbirth. There are Grades 0-4 of this condition. Describe them.
Grade 0: no descent
Grade 1: uterus descent into the upper 2/3 of the vagina
Grade 2: the cervix approaches the introitus
Grade 3: the cervix is outside the introitus
Grade 4: entire uterus is outside the vagina
Treatment for uterine prolapse
- Mechanical: pessaries elevate and support uterus
- Surgical: Hysterectomy or ligament fixation
What is Peyronie Disease?
-Acquired localized fibrotic changes of the tunica albuginea leading to abnormal penile curvature
Treatment for Peyronie Disease
- Observation: if curvature is 30 degrees or less
- Medical: if curvature 30 degrees or more or associated with sexual dysfunction
What is vesicoureteral reflux?
-Retrograde passage of urine from the bladder into the upper urinary tract
MC clinical manifestation of VUR
-Febrile UTI
What is the initial diagnostic that is usually ordered for VUR and what is the diagnostic that is the imaging test of choice?
- Renal and bladder US (initial)
- Voiding cystourethrogram (diagnostic of choice)
Treatment for VCUG, for all grades
- Grades I-II: observation or ABX prophylaxis to reduce risk of recurrent UTI
- Grades III - IV: surgical correction
MCC of acute cystitis
-E. Coli
However, what is the most common cause of acute cystitis in sexually active women?
Staph Saprophyticus