Cardiology #1 Flashcards
Dilated cardiomyopathy is MCC by what things?
Idiopathic, Coxsackievirus, Alcohol, Cocaine, B1 deficiency
Symptoms of Dilated cardiomyopathy
S3 gallop, heart failure symptoms
Diagnostics for dilated cardiomyopathy
-Echo (LV dilation), CXR (cardiomegaly)
Treatment for dilated cardiomyopathy
ACE, ARB, BB, Spironolactone, Diuretics, AICD if EF < 35%
Stress cardiomyopathy is the result of what
Catecholamine surge during stress (such as postmenopausal, death of family member)
-Transient regional systolic dysfunction of the left ventricle in absence of significant obstructive coronary artery disease or evidence of plaque rupture.
Treatment for stress cardiomyopathy
Aspirin + BB + Nitro + Heparin (mimics MI)
Supportive care is mainstay of treatment (BB or ACE for 3-6 months with serial imaging to assess for improvement)
What is on history of a patient with restrictive cardiomyopathy?
Infiltrative disease (amyloidosis, sarcoidosis, scleroderma)
Diagnostics for restrictive cardiomyopathy
- Echo (initially) - diastolic dysfunction and marked dilation of both atria
- Endomyocardial biopsy (definitive)
Hypertrophic cardiomyopathy pathophysiology
Diastolic dysfunction due to inappropriate LV and RV hypertrophy
What does an Echo for hypertrophic cardiomyopathy show?
- Asymmetric ventricular wall thickness (especially septal), 15 mm or greater
- Small LV chamber size
Treatment for hypertrophic cardiomyopathy
BB
If no response, myomectomy performed or alcohol septal ablation.
What does the murmur for hypertrophic cardiomyopathy sound like?
Harsh systolic murmur at LSB, Loud S4
- Increased intensity with standing, Valsalva
- Decreased intensity with squatting, supine
Myocarditis is MCC by
-Enterovirus (Coxsackievirus), Clozapine
Symptoms of Myocarditis
- Viral prodrome followed by systolic dysfunction
- S3 gallop
- Pericarditis
- Megacolon
Diagnostics for myocarditis
- CXR: cardiomegaly
- Echo: Ventricular systolic dysfunction
- Endomyocardial biopsy: gold
Treatment for myocarditis
- Supportive (systolic heart failure treatment)
- ACE/Diuretics/BB
Treatment for sinus tachycardia
- BB if they have ACS
- Otherwise, treat the underlying cause (first line)
Treatment for sinus bradycardia
- Atropine is symptomatic
- If asymptomatic, no treatment needed
What is sick sinus syndrome
Sinus arrest alternating paroxysms of tachycardia and bradycardia
Treatment for sick sinus syndrome
- Stable: may not need treatment, often transient
- Atropine if needed
- Long term: pacemaker + ICD if alternating between tachycardia and bradycardia
What defines a first-degree AV block
- Prolonged PR interval, but all followed by QRS complex
- PR Interval is > 0.20 seconds
Treatment for first-degree AV block
Atropine is first-line if symptomatic
-If asymptomatic, no treatment, observation.
-Pacemaker is definitive, if persistent or PRI > 0.30 seconds
What defines a second-degree AV block (Type I)
progressive lengthening of PR interval, dropped QRS complex
-This is known as a Wenkebach
Treatment for second-degree AV block
-Atropine, Pacemaker definitive
Causes for second-degree AV block Type I
Inferior Wall MI, AV nodal blocking agents (BB, CCB, Lyme Disease)
What defines a second-degree AV block (Type II)
Constant PR interval before and after dropped QRS complex
Treatment for Mobitz Type II
Transcutaneous pacing or Atropine
-Permanent Pacemaker for long-term
What defines a third degree AV block
Regular P-P intervals and R-R intervals but they are not related to each other
(AV Dissociation)
Treatment for 3rd degree AV block
Transcutaneous pacing followed by permanent pacemaker
Treatment for Atrial Flutter
Vagal maneuvers, BB, CCB
- Unstable: Direct current synchronized cardioversion
- Radiofrequency catheter ablation (definitive)
Symptoms of atrial fibrillation
Hypotension, AMS, refractory chest pain
What does an ECG show for atrial fibrillation?
What is Ashman’s Phenomenon on ECG?
Irregularly irregular rhythm with fibrillary waves (no discrete P waves)
-Occasional aberrantly conducted beats (wide QRS) after short R-R cycles
Treatment for stable atrial fibrillation
BB, CCB (Diltiazem, Verapamil)
-Digoxin only used when BB and CCB are contraindicated (CHF or severe hypotension)
Treatment for unstable A-fib
direct current synchronized cardioversion
-Echo needed prior to tell if there are atrial clots
Treatment for A-Fib determined by time present. Explain
- AF > 48 hours: anticoagulation for 3 weeks
- AF < 48 hours: elective cardioversion, anticoagulation for 4 weeks
What is the definitive treatment for A-Fib
Radiofrequency catheter ablation
Regarding the CHA2DS2-VASc score, a score of 2 or greater needs chronic anticoagulation. Explain this score.
Congestive heart failure (1) Hypertension (1) Age > 75 (2) Diabetes (1) Stroke (2) Vascular event such as MI, PAD (1) Age 65-74 (1) Sex Female (1)
What does an ECG for Paroxysmal Supraventricular Tachycardia show?
regular, narrow QRS tachycardia with no discernible P waves
Treatment or SVT
Vagal maneuvers, Adenosine
- Unstable: Direct current synchronized cardioversion
- Definitive: Radiofrequency catheter ablation
Three components of Wolff-Parkinson White Syndrome
Pathophysiology of WPW
Delta wave, shortened PR, wide QRS
-Accessory pathway (Bundle of Kent) preexcites the ventricles and leads to a delta wave
Treatment for WPW
- Stable (Procainamide)
- Unstable (Cardioversion)
- Definitive: Catheter Ablation
Treatment for Torsades de Pointes
IV Magnesium Sulfate
Treatment for V-fib
Unsynchronized cardioversion (Defibrillate) + CPR
Treatment for V-tach
- Stable: Amiodarone
- Unstable: Direct current synchronized cardioversion
Define a LBBB
R and R1 (upward bunny ears) in V4-V6
STEMI Equivalent
Define a RBBB
-R1 and R1 in V1-V3 Upward bunny ears
Best test for Patent Foramen Ovale
Echo
What is a patent foramen ovale?
Unsealed opening between RA and LA
MC type of ASD
Ostium Secundum
Murmur of ASD
-Systolic ejection crescendo-decrescendo flow murmur at LUSB with wide, fixed split S2 that does not vary with respiration
Diagnostics for ASD
- Echo
- Catheter (Definitive)
Treatment for ASD
- < 5 mm may be observed
- > 1 cm surgical correction
What is a patent ductus arteriosus
-Persistent communication between descending thoracic aorta and main pulmonary artery
Murmur of PDA
-Continuous machine like murmur loudest at pulmonic area
Diagnostics for PDA
- Echo
- Catheter (Definitive)
Treatment for PDA
- NSAIDs
- Indomethacin
Symptoms of Coarctation of Aorta
-Bilateral claudication, syncope, DOE, failure to thrive, poor feeding, upper extremity hypertension with lower extremity hypotension
Murmur of Coarctation of Aorta
-Systolic murmur radiating to back, scapula, or chest
Diagnostics for Coarctation of Aorta
- CXR: rib notching, figure 3 sign
- Echo
- Angiography (gold)
Treatment for Coarctation of Aorta
- Prostaglandin E1 preoperatively
- Corrective surgery
Four factors of Tetralogy of Fallot
- Pulmonary stenosis
- RVH
- Overriding Aorta
- VSD
Symptoms of ToF
- Tet spells (relieved with squatting)
- Cyanosis
Murmur of ToF
-harsh systolic murmur at Upper sternal border (VSD) and right ventricular heave
Diagnostics for ToF
- Echo (diagnostic of choice)
- CXR (boot shaped heart)
Treatment for ToF
- Prostaglandin E1 preoperatively
- Surgical repair
Pathophysiology of Transposition of Great arteries
-What is the MC type of ToGA?
- Aorta arises from RV and pulmonary trunk from LV
- Dextro-TGA: prior to surgical correction, survival dependent on presence of shunts between right and left circulations (PDA, ASD, VSD)
Diagnostics for Transposition
- Echo
- CXR (egg on string)
- Catheter (gold)
MC congenital heart disease in children
VSD
Murmur of VSD
-High pitched harsh holosystolic murmur at LLSB
Order of ECG strip
I avR V1 V4
II avL V2 V5
III avF V3 V6
Anterior Wall and Septal MI corresponds to which artery
LAD
Inferior Wall MI corresponds to what artery
RCA
Lateral Wall MI corresponds to which artery
LCA
What is stress cardiomyopathy in regards to ventricles?
-Transient regional systolic dysfunction of the left ventricle that can imitate MI but in absence of significant obstructive CAD or plaques
Risk Factors for Stress Cardiomyopathy
- Postmenopausal women
- Exposure to emotional or physical stress
- Death of relative, etc.